Category: News
Rejuvenation Roundup November 2018
December 3, 2018
‘Tis the season to be jolly, friends of healthy longevity! Time to dim the lights, gather around a crackling fireplace, cuddle up into a warm blanket, and recap the rejuvenation
Would I Want a Designer Baby? CRISPR, Gene-Editing, and You
November 29, 2018
A couple of days ago, news about the first designer babies has shaken the world. A Chinese researcher, Jiankui He, and his team at the Southern University of Science and
A Review of Fasting and Calorie Restriction
November 28, 2018
Today, we want to discuss a review published in the journal Science, as it provides a whistle-stop tour of caloric restriction, intermittent fasting, and time-restricted feeding [1]. There is a
Too much mTOR is Linked to Diabetes and Aging
November 15, 2018
A new study takes a look at the relationship between metabolism, aging, and type 2 diabetes and in particular the mTORC1 protein complex, part of the mTOR pathway. The mTOR
An Interview With Leonid Gavrilov And Natalia Gavrilova
November 14, 2018
Many people are concerned that vastly extended healthy lifespan might lead us to catastrophic overpopulation, and the best way to mitigate this fear is probably to talk to an experienced
Plasma NAD+ Levels Decline Significantly with Age
November 9, 2018
Today, we want to highlight a recent, small-scale study looking at NAD+ and how it declines with age in the plasma. The researchers looked at various NAD+ metabolites across age
Lab on a Chip Measures Aging Biomarkers Almost Instantly
November 7, 2018
A new palm-sized testing system has been developed to measure the levels of aging biomarkers circulating in the body. The new biomarker system, called Click-A+Chip, was developed by Sarah Balderston
Drug that Slows Alzheimer’s Successful
November 6, 2018
Through a new approach dubbed AMBAR, the biotechnology company Grifols has attempted to reduce the amount of harmful, Alzheimer’s disease-causing amyloid beta in the brain by collecting it with a
The Young Turks Interview Keith Comito
November 5, 2018
As part of our strategy, we are constantly networking and seeking opportunities to engage new audiences about the topic of healthy life extension. Recently our President, Keith Comito appeared on
Choosing Health Early On
November 2, 2018
Today, we’re going to engage in a thought experiment. We’re going to imagine a world with some sort of antechamber to life in which you hang around as some sort
Rejuvenation Roundup October 2018
November 1, 2018
Longevity Month is behind us, and the holiday season lies ahead; to set the mood, what could be better than sitting down comfortably with your favorite hot drink and reading
NAD+ and Longevity – Dr. David Sinclair AMA
October 25, 2018
On the 23rd of this month, Dr. David Sinclair did an Ask Me Anything over at the Futurology subreddit in support of the NAD+ Mouse Project on lifespan.io. There were
Protein Produced by Astrocytes Involved in Brain Plasticity
October 23, 2018
Researchers from the Salk Institute have discovered that a protein called Chrdl1, secreted by astrocytes, is responsible for driving synapse maturation and limiting brain plasticity later in life [1]. Abstract
Dr. Sam Palmer – Thymic Involution and Cancer Risk
October 22, 2018
Cancer is the poster child of age-related diseases, and a recent study sheds light on why the risk of cancer rises dramatically as we age. Abstract For many cancer types,
Reason and Bill Cherman – Investing in Longevity
October 9, 2018
Here at LEAF, we engage in a wide range of activities in support of the development of rejuvenation biotechnology in order to end age-related diseases. We report the latest news
Rejuvenation Roundup November 2018
December 3, 2018
‘Tis the season to be jolly, friends of healthy longevity! Time to dim the lights, gather around a crackling fireplace, cuddle up into a warm blanket, and recap the rejuvenation news of last November. LEAF News Highlight: Keith at The Young Turks LEAF President Keith Comito
Would I Want a Designer Baby? CRISPR, Gene-Editing, and You
November 29, 2018
A couple of days ago, news about the first designer babies has shaken the world. A Chinese researcher, Jiankui He, and his team at the Southern University of Science and Technology of China have been recruiting couples in order to create the world’s first babies with
A Review of Fasting and Calorie Restriction
November 28, 2018
Today, we want to discuss a review published in the journal Science, as it provides a whistle-stop tour of caloric restriction, intermittent fasting, and time-restricted feeding [1]. There is a considerable amount of data supporting the effects of caloric restriction and similar dietary approaches on both
Too much mTOR is Linked to Diabetes and Aging
November 15, 2018
A new study takes a look at the relationship between metabolism, aging, and type 2 diabetes and in particular the mTORC1 protein complex, part of the mTOR pathway. The mTOR pathway The mechanistic target of rapamycin (mTOR) pathway is a major part of metabolism and is
An Interview With Leonid Gavrilov And Natalia Gavrilova
November 14, 2018
Many people are concerned that vastly extended healthy lifespan might lead us to catastrophic overpopulation, and the best way to mitigate this fear is probably to talk to an experienced demographer. To learn more about this and other interesting questions related to life extension, we spoke
Plasma NAD+ Levels Decline Significantly with Age
November 9, 2018
Today, we want to highlight a recent, small-scale study looking at NAD+ and how it declines with age in the plasma. The researchers looked at various NAD+ metabolites across age groups and found that the amounts of some of them, particularly NAD+ itself, are significantly smaller
Lab on a Chip Measures Aging Biomarkers Almost Instantly
November 7, 2018
A new palm-sized testing system has been developed to measure the levels of aging biomarkers circulating in the body. The new biomarker system, called Click-A+Chip, was developed by Sarah Balderston and Mandeep Sandhu, who are part of the Keck Graduate Institute team led by Assistant Professor
Drug that Slows Alzheimer’s Successful
November 6, 2018
Through a new approach dubbed AMBAR, the biotechnology company Grifols has attempted to reduce the amount of harmful, Alzheimer’s disease-causing amyloid beta in the brain by collecting it with a blood protein called albumin and draining it out of the bloodstream. This approach differs from the
The Young Turks Interview Keith Comito
November 5, 2018
As part of our strategy, we are constantly networking and seeking opportunities to engage new audiences about the topic of healthy life extension. Recently our President, Keith Comito appeared on the Young Turks Rebel HQ and spoke with Cenk Uygur, the host, and creator of the
Choosing Health Early On
November 2, 2018
Today, we’re going to engage in a thought experiment. We’re going to imagine a world with some sort of antechamber to life in which you hang around as some sort of disembodied entity before you are born. (Some people actually believe in something like that, but
Rejuvenation Roundup October 2018
November 1, 2018
Longevity Month is behind us, and the holiday season lies ahead; to set the mood, what could be better than sitting down comfortably with your favorite hot drink and reading the latest updates from the world of rejuvenation? Let’s get started. LEAF News Highlight: the NAD+
NAD+ and Longevity – Dr. David Sinclair AMA
October 25, 2018
On the 23rd of this month, Dr. David Sinclair did an Ask Me Anything over at the Futurology subreddit in support of the NAD+ Mouse Project on lifespan.io. There were a range of interesting questions from the community about his work in aging research, particularly the
Protein Produced by Astrocytes Involved in Brain Plasticity
October 23, 2018
Researchers from the Salk Institute have discovered that a protein called Chrdl1, secreted by astrocytes, is responsible for driving synapse maturation and limiting brain plasticity later in life [1]. Abstract In the developing brain, immature synapses contain calcium-permeable AMPA glutamate receptors (AMPARs) that are subsequently replaced
Dr. Sam Palmer – Thymic Involution and Cancer Risk
October 22, 2018
Cancer is the poster child of age-related diseases, and a recent study sheds light on why the risk of cancer rises dramatically as we age. Abstract For many cancer types, incidence rises rapidly with age as an apparent power law, supporting the idea that cancer is
Reason and Bill Cherman – Investing in Longevity
October 9, 2018
Here at LEAF, we engage in a wide range of activities in support of the development of rejuvenation biotechnology in order to end age-related diseases. We report the latest news in aging research, attend conferences and give talks, educate, advocate, and fundraise for research projects on