Category: News
David Sinclair on Human Trials of Anti-Aging Compounds
January 9, 2024
A new review authored by three acclaimed geroscientists paints a promising picture of past and ongoing human clinical trials of prospective anti-aging drugs [1]. From worms and mice to humans
Treating Arthritis with Rapamycin-Releasing Nanoparticles
January 8, 2024
Researchers have described how specialized nanoparticles, which deliver rapamycin and the antioxidant astaxanthin, restore macrophage balance and reduce inflammation in a mouse model of osteoarthritis. A matter of polarization Inflammation
TLR5 Activation Improves Health and Lifespan in Aged Mice
January 5, 2024
By activating toll-like receptor 5, an important element of the innate immune system, scientists have increased lifespan and improved multiple health measurements in old mice, despite having started the treatment
Mikhail Batin’s Crusade Against Aging
January 4, 2024
There’s no other way to put it: Mikhail (Misha) Batin is an oddball in the longevity space. In this field, which is populated mostly by scientists, entrepreneurs, and enthusiasts, Batin
A Carrot Extract Improves the Metabolism of Old Mice
January 4, 2024
In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric
Female-Specific Aging Trajectories Remain Understudied
January 3, 2024
In a recent Perspective published in Nature Aging, researchers noted a lack of studies on female-specific physiological factors on aging trajectories. They proposed solutions, including model systems, to address the
Study Suggests Trade-Offs Between Reproduction and Lifespan
January 2, 2024
Scientists might have found support for the antagonistic pleiotropy theory of aging, which suggests that evolution selects some genetic traits that are associated with shorter lifespans because they also help
Rejuvenation Roundup December 2023
January 2, 2024
The holidays are over, and a new year has begun! However, festive celebrations weren’t the only things happening last month. Here’s the rejuvenation research and biotech developments that took place
Best Christmas Wishes from lifespan.io
December 28, 2023
The holidays are here, and it’s time for a well-earned rest and some festive fun with family and friends! We will take a look at what the lifespan.io team has
Longevity Investor Network 2023 End of Year Update
December 27, 2023
The Longevity Investor Network has experienced significant growth and success over the past year. Our mission to connect innovative companies in the longevity sector with forward-thinking investors has seen remarkable
U-Shaped Association With Vigorous Exercise and Alzheimer’s
December 22, 2023
According to a new study, the amount of leisure time spent on vigorous physical activity is inversely correlated with Alzheimer’s, but after a certain point, the association is reversed [1].
A New Anti-Inflammatory Approach for Arthritis
December 21, 2023
In Aging, researchers have published their tests of a compound that counteracts the effects of tumor necrosis factor alpha (TNF-α), an inflammatory factor that promotes arthritis. Current anti-inflammatories aren’t enough
Morning Exercise May Be Better Against Metabolic Syndrome
December 20, 2023
In a recent paper published in The Journal of Physiology, researchers compared the impacts of morning and afternoon aerobic exercise for people with metabolic syndrome [1]. Hitting the gym after
David Sinclair Presents His Information Theory of Aging
December 19, 2023
In a new paper, Sinclair and his co-authors outline a theory arguing that epigenetic changes are the underlying cause of aging [1]. When cells get old It is not every
A Clinical Trial of Neural Stem Cells for MS
December 18, 2023
In Cell Stem Cell, researchers have published the results of a Phase 1 clinical trial of a treatment that uses neural stem cells (NSCs) to treat multiple sclerosis. Looking for
David Sinclair on Human Trials of Anti-Aging Compounds
January 9, 2024
A new review authored by three acclaimed geroscientists paints a promising picture of past and ongoing human clinical trials of prospective anti-aging drugs [1]. From worms and mice to humans The biology of aging is an exciting new field, but most of its successes have been
Treating Arthritis with Rapamycin-Releasing Nanoparticles
January 8, 2024
Researchers have described how specialized nanoparticles, which deliver rapamycin and the antioxidant astaxanthin, restore macrophage balance and reduce inflammation in a mouse model of osteoarthritis. A matter of polarization Inflammation is a critical part of arthritis. Previous studies have found that inflammation of the membranes in
TLR5 Activation Improves Health and Lifespan in Aged Mice
January 5, 2024
By activating toll-like receptor 5, an important element of the innate immune system, scientists have increased lifespan and improved multiple health measurements in old mice, despite having started the treatment late in life [1]. TLRs and aging The immune system gets dysregulated with age, driving multiple
Mikhail Batin’s Crusade Against Aging
January 4, 2024
There’s no other way to put it: Mikhail (Misha) Batin is an oddball in the longevity space. In this field, which is populated mostly by scientists, entrepreneurs, and enthusiasts, Batin belongs to a different breed: activists. But, even among this small group, Batin is one of
A Carrot Extract Improves the Metabolism of Old Mice
January 4, 2024
In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric restriction pathway Although it is difficult to establish in human beings, caloric restriction is one of
Female-Specific Aging Trajectories Remain Understudied
January 3, 2024
In a recent Perspective published in Nature Aging, researchers noted a lack of studies on female-specific physiological factors on aging trajectories. They proposed solutions, including model systems, to address the issue [1]. Most model organisms don’t match human sex specificity The use of model organisms, such
Study Suggests Trade-Offs Between Reproduction and Lifespan
January 2, 2024
Scientists might have found support for the antagonistic pleiotropy theory of aging, which suggests that evolution selects some genetic traits that are associated with shorter lifespans because they also help us reproduce [1]. Evolution needs you to reproduce, not live long Shouldn’t evolution favor longer lifespans,
Rejuvenation Roundup December 2023
January 2, 2024
The holidays are over, and a new year has begun! However, festive celebrations weren’t the only things happening last month. Here’s the rejuvenation research and biotech developments that took place in December. LEAF News Best Christmas Wishes from lifespan.io: In this holiday missive, we took a
Best Christmas Wishes from lifespan.io
December 28, 2023
The holidays are here, and it’s time for a well-earned rest and some festive fun with family and friends! We will take a look at what the lifespan.io team has been up to recently, so sit back, relax, and enjoy a mince pie while you read
Longevity Investor Network 2023 End of Year Update
December 27, 2023
The Longevity Investor Network has experienced significant growth and success over the past year. Our mission to connect innovative companies in the longevity sector with forward-thinking investors has seen remarkable achievements, particularly in 2023. Investors On the investor side, we have now over 200 longevity investors
U-Shaped Association With Vigorous Exercise and Alzheimer’s
December 22, 2023
According to a new study, the amount of leisure time spent on vigorous physical activity is inversely correlated with Alzheimer’s, but after a certain point, the association is reversed [1]. Outrunning dementia Due to populational aging and medicine’s successes against other age-related diseases, Alzheimer’s disease has
A New Anti-Inflammatory Approach for Arthritis
December 21, 2023
In Aging, researchers have published their tests of a compound that counteracts the effects of tumor necrosis factor alpha (TNF-α), an inflammatory factor that promotes arthritis. Current anti-inflammatories aren’t enough Rheumatoid arthritis, an autoimmune disorder that causes joint swelling, pain, and disability, is most often treated
Morning Exercise May Be Better Against Metabolic Syndrome
December 20, 2023
In a recent paper published in The Journal of Physiology, researchers compared the impacts of morning and afternoon aerobic exercise for people with metabolic syndrome [1]. Hitting the gym after breakfast or after lunch Metabolic syndrome (MetS) has been defined as a group of “cardiometabolic risk
David Sinclair Presents His Information Theory of Aging
December 19, 2023
In a new paper, Sinclair and his co-authors outline a theory arguing that epigenetic changes are the underlying cause of aging [1]. When cells get old It is not every day that one of the most prominent geroscientists presents a new theory of aging. David Sinclair
A Clinical Trial of Neural Stem Cells for MS
December 18, 2023
In Cell Stem Cell, researchers have published the results of a Phase 1 clinical trial of a treatment that uses neural stem cells (NSCs) to treat multiple sclerosis. Looking for better therapies Multiple sclerosis (MS) is a progressive disease that afflicts approximately two million people worldwide