Category: News
Mechanically Reprogrammed Fibroblasts for Skin Rejuvenation
December 4, 2023
Scientists have found a way to reprogram fibroblasts without chemicals by culturing them on a surface with specific mechanical properties. Transplanted into aged skin, those cells boosted rejuvenation in a
Longevity and DeSci Recap – November 2023
December 1, 2023
Thanks for joining us again for the latest edition of the Longevity and DeSci Recap. This month’s highlights include fantastic conferences, such as the Rejuvenation Startup Summit 2024 in Berlin,
Healthy Diet Linked to Massive Gains in Life Expectancy
December 1, 2023
A new study has found that switching to longevity-associated dietary patterns was associated with up to a 10-year gain in life expectancy for 40-year-olds and up to a 3.4-year gain
Rejuvenation Roundup November 2023
December 1, 2023
As researchers and biotech companies continue to work on the therapies and technologies that may let people live longer lives, much other research tells us about the lifestyle habits that
Running Is Associated With Better Health Biomarkers
November 30, 2023
In a recent publication in PLOS One, researchers have described the metabolic effects on running in generally healthy people. A lack of activity is a known risk factor This paper
Music Therapy for Treating Alzheimer’s Disease
November 29, 2023
The authors of a new review have analyzed randomized controlled trials that evaluated the impact of music therapy on the cognitive functions of people with Alzheimer’s [1]. Music to Alzheimer’s
Isoleucine Restriction Boosts Lifespan in Mice
November 28, 2023
A new study reports a massive 33% increase in median lifespan in male genetically heterogeneous mice following prolonged isoleucine restriction [1]. Not all calories are created equal Caloric restriction is
Mammals Accumulate Epigenetic Noise With Age
November 27, 2023
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We have previously reported on research demonstrating
B12 Is a Limiting Factor for Induced Cellular Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the lifespan.io Facebook channel and hosted
Journal Club Nov – B12 and Cell Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the lifespan.io Facebook channel and hosted
Predicting a Species’ Longevity Through Epigenetics
November 26, 2023
A preprint study published on bioRxiv discusses how a species’ maximum lifespan can be predicted by its epigenetics, showing that these differences are largely unaffected by interventions. Differences and similarities
Aging Might Blunt the Effects of Fasting
November 24, 2023
Scientists have found that in killifish, old age is associated with a dampened response to fasting and identified the protein that might be responsible. A similar mechanism might exist in
Some HIV-Fighting Drugs May Also Fight Aging
November 23, 2023
Publishing in Ageing Research Reviews, a team of researchers including Vera Gorbunova has described how a class of drugs originally used to treat HIV might be used to affect some
Dual-Purpose Molecular Targets for Cancer and Aging
November 22, 2023
A new study published in Aging Cell applied an artificial intelligence target discovery platform to aid in identifying potential dual-purpose targets for anti-aging and anti-cancer treatments [1]. Killing two birds
Young People More Vulnerable to Atherosclerosis Risk Factors
November 21, 2023
A new study suggests that increases in LDL cholesterol and systolic blood pressure elevate the risk of atherosclerosis progression more in younger than in older people. The good news is
Mechanically Reprogrammed Fibroblasts for Skin Rejuvenation
December 4, 2023
Scientists have found a way to reprogram fibroblasts without chemicals by culturing them on a surface with specific mechanical properties. Transplanted into aged skin, those cells boosted rejuvenation in a human tissue model [1]. We’ve all got skin in the game Skin aging might not be
Longevity and DeSci Recap – November 2023
December 1, 2023
Thanks for joining us again for the latest edition of the Longevity and DeSci Recap. This month’s highlights include fantastic conferences, such as the Rejuvenation Startup Summit 2024 in Berlin, the Vitalia event in Roatan, and the large-scale Longevity Med Summit in Lisbon, along with many
Healthy Diet Linked to Massive Gains in Life Expectancy
December 1, 2023
A new study has found that switching to longevity-associated dietary patterns was associated with up to a 10-year gain in life expectancy for 40-year-olds and up to a 3.4-year gain for 70-year-olds [1]. Eat your way to longevity Since the early twentieth century, average human life
Rejuvenation Roundup November 2023
December 1, 2023
As researchers and biotech companies continue to work on the therapies and technologies that may let people live longer lives, much other research tells us about the lifestyle habits that people are doing to lengthen them – or shorten them – in the meantime. Here’s what
Running Is Associated With Better Health Biomarkers
November 30, 2023
In a recent publication in PLOS One, researchers have described the metabolic effects on running in generally healthy people. A lack of activity is a known risk factor This paper begins with warnings against sedentary behavior, citing one study reporting that it is responsible for approximately
Music Therapy for Treating Alzheimer’s Disease
November 29, 2023
The authors of a new review have analyzed randomized controlled trials that evaluated the impact of music therapy on the cognitive functions of people with Alzheimer’s [1]. Music to Alzheimer’s patients’ ears Current pharmacology lacks a long-term method of effectively managing Alzheimer’s disease symptoms. Therefore, researchers
Isoleucine Restriction Boosts Lifespan in Mice
November 28, 2023
A new study reports a massive 33% increase in median lifespan in male genetically heterogeneous mice following prolonged isoleucine restriction [1]. Not all calories are created equal Caloric restriction is the most powerful life-extending intervention in rodents and primates [2], but the needed magnitude (about 30%
Mammals Accumulate Epigenetic Noise With Age
November 27, 2023
In Nature Communications, researchers have explained how epigenetic drift and disorder are associated with shorter lifespans across species. When randomness is a problem We have previously reported on research demonstrating that epigenetic clocks are most likely to be measuring noise. This paper builds on that concept,
B12 Is a Limiting Factor for Induced Cellular Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the lifespan.io Facebook channel and hosted by Dr. Oliver Medvedik. This month, we will be taking a look at a new paper
Journal Club Nov – B12 and Cell Plasticity
November 27, 2023
Due to Thanksgiving happening on our usual timeslot, the Journal Club returns on December 1st at 12 Eastern. The show will be livestreamed on the lifespan.io Facebook channel and hosted by Dr. Oliver Medvedik. This month we will be taking a look at a new paper
Predicting a Species’ Longevity Through Epigenetics
November 26, 2023
A preprint study published on bioRxiv discusses how a species’ maximum lifespan can be predicted by its epigenetics, showing that these differences are largely unaffected by interventions. Differences and similarities in mammals The researchers begin their paper with a note that bowhead whales live over a
Aging Might Blunt the Effects of Fasting
November 24, 2023
Scientists have found that in killifish, old age is associated with a dampened response to fasting and identified the protein that might be responsible. A similar mechanism might exist in humans [1]. Fast less furious Various fasting regimens are thought to confer health and longevity benefits
Some HIV-Fighting Drugs May Also Fight Aging
November 23, 2023
Publishing in Ageing Research Reviews, a team of researchers including Vera Gorbunova has described how a class of drugs originally used to treat HIV might be used to affect some of the hallmarks of aging. Inhibiting DNA changes DNA transcription, which transfers DNA code into the
Dual-Purpose Molecular Targets for Cancer and Aging
November 22, 2023
A new study published in Aging Cell applied an artificial intelligence target discovery platform to aid in identifying potential dual-purpose targets for anti-aging and anti-cancer treatments [1]. Killing two birds with one stone Aging, as is the case with many diseases, is a risk factor for
Young People More Vulnerable to Atherosclerosis Risk Factors
November 21, 2023
A new study suggests that increases in LDL cholesterol and systolic blood pressure elevate the risk of atherosclerosis progression more in younger than in older people. The good news is that this can be reversed [1]. Creeping atherosclerosis Atherosclerosis is a major risk factor for cardiovascular