Category: News
Remembering Where We Are in Alzheimer’s Research
October 22, 2023
A pair of neurologists have published a review in Cell discussing the current state of Alzheimer’s therapies, including drugs in early development, treatments in clinical trials, and therapies that are
High-Protein Diets Have Few Benefits in Mice
October 20, 2023
A new study suggests that high protein intake leads to fat gain and worse metabolic outcomes, but some of these effects are blocked by resistance training. Low protein consumption resulted
DNA Damage And Aging Of The Blood Vessels
October 19, 2023
In a paper published in Aging, researchers have explored the relationship between DNA damage and aging of the blood vessels. How arteries age This paper begins with some well-known facts
Treating Hypertension May Reduce Dementia Risk
October 18, 2023
Research published in JAMA Geriatrics analyzed the link between blood pressure, hypertension, and the risk of dementia [1]. Inconsistent research Published research is inconsistent regarding the link between hypertension and
The Longevity World Meets in Dublin for a Second Time
October 17, 2023
Last year’s inaugural Longevity Summit Dublin conference was a good start. Its second iteration, held in August this year, was universally acclaimed for being even bigger and better. Just like
Spermidine May Improve Egg Health and Fertility
October 16, 2023
Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm
Study Suggests a New Mechanism of Cellular Senescence
October 13, 2023
Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1].
Why Long-Lived Animals Are Needed for Life Extension Studies
October 12, 2023
A team of researchers, including Matt Kaeberlein and Brian Kennedy, has published a preprint discussing the necessity of using long-lived animals in life extension research. The Interventions Testing Program (ITP)
Correlations Between Omega-3 Fatty Acids and Brain Function
October 11, 2023
The authors of a study published in Brain Sciences have investigated the relationship between omega-3 fatty acid levels, brain volume, and cognitive function [1]. Aging and changes in the brain With
Journal Club October 2023 with Irina and Mike Conboy
October 11, 2023
The Journal Club returns on Friday October 27th at 11:30 am Eastern time on the lifespan.io Facebook page. We will be discussing the new paper from Conboy et al. which
Help Us Solve Aging With Cryptocurrency
October 10, 2023
If you want to contribute to lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We
SIRT2 Works Against Cardiac Aging in Mice and Monkeys
October 10, 2023
Working with non-human primates, scientists have discovered that the protein SIRT2, a member of the sirtuin family, might play an important role in slowing cardiac aging [1]. The heart of
A Mutation Rejuvenates Memory in Worms and Mice
October 9, 2023
A study published in Cell Reports has shown how the activation of a common protein in neurons improves memory in both worms and mammals. Common between animals This paper begins
Dublin Longevity Declaration Off to a Good Start
October 6, 2023
The Dublin Longevity Declaration, an unprecedented initiative that aims to change humanity’s perception of aging, is scooping signatures at a record pace. The need for a paradigm shift Last August,
Improving Quality and Length of Life with Stem Cells
October 5, 2023
A review article published in Stem Cell Research & Therapy has described the ways in which mesenchymal stromal cells (MSCs) are being developed to treat diseases, including age-related diseases. A
Remembering Where We Are in Alzheimer’s Research
October 22, 2023
A pair of neurologists have published a review in Cell discussing the current state of Alzheimer’s therapies, including drugs in early development, treatments in clinical trials, and therapies that are prescribed today. The -mab drugs Monoclonal antibodies, drugs whose names end in -mab, have become the
High-Protein Diets Have Few Benefits in Mice
October 20, 2023
A new study suggests that high protein intake leads to fat gain and worse metabolic outcomes, but some of these effects are blocked by resistance training. Low protein consumption resulted in less muscle gain but did not affect strength [1]. The protein debate One of the
DNA Damage And Aging Of The Blood Vessels
October 19, 2023
In a paper published in Aging, researchers have explored the relationship between DNA damage and aging of the blood vessels. How arteries age This paper begins with some well-known facts about aging and cardiovascular risk. Cardiovascular disease is the single most common cause of death in
Treating Hypertension May Reduce Dementia Risk
October 18, 2023
Research published in JAMA Geriatrics analyzed the link between blood pressure, hypertension, and the risk of dementia [1]. Inconsistent research Published research is inconsistent regarding the link between hypertension and dementia. Some studies suggest an association between midlife hypertension and increased dementia risk. Other studies have
The Longevity World Meets in Dublin for a Second Time
October 17, 2023
Last year’s inaugural Longevity Summit Dublin conference was a good start. Its second iteration, held in August this year, was universally acclaimed for being even bigger and better. Just like the last time, this conference was marked by a considerable presence of longevity advocates alongside scientists
Spermidine May Improve Egg Health and Fertility
October 16, 2023
Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm While it was originally found in semen, the metabolite spermidine has been found in many different
Study Suggests a New Mechanism of Cellular Senescence
October 13, 2023
Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1]. A new aspect of senescence Clearing senescent cells with drugs called senolytics is one of the
Why Long-Lived Animals Are Needed for Life Extension Studies
October 12, 2023
A team of researchers, including Matt Kaeberlein and Brian Kennedy, has published a preprint discussing the necessity of using long-lived animals in life extension research. The Interventions Testing Program (ITP) uncovers weaknesses The ITP is run by the National Institutes of Aging and described by these
Correlations Between Omega-3 Fatty Acids and Brain Function
October 11, 2023
The authors of a study published in Brain Sciences have investigated the relationship between omega-3 fatty acid levels, brain volume, and cognitive function [1]. Aging and changes in the brain With aging comes progressive changes in brain structure and ra eduction in cognitive abilities. The first changes
Journal Club October 2023 with Irina and Mike Conboy
October 11, 2023
The Journal Club returns on Friday October 27th at 11:30 am Eastern time on the lifespan.io Facebook page. We will be discussing the new paper from Conboy et al. which examines current DNA methylation clocks and their limitations in the context of aging. They also developed
Help Us Solve Aging With Cryptocurrency
October 10, 2023
If you want to contribute to lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We promote the advancement of medical technologies that will increase healthy human longevity. By sponsoring, democratizing, and
SIRT2 Works Against Cardiac Aging in Mice and Monkeys
October 10, 2023
Working with non-human primates, scientists have discovered that the protein SIRT2, a member of the sirtuin family, might play an important role in slowing cardiac aging [1]. The heart of the matter The heart is arguably the hardest worker among the organs, constantly pumping enormous amounts
A Mutation Rejuvenates Memory in Worms and Mice
October 9, 2023
A study published in Cell Reports has shown how the activation of a common protein in neurons improves memory in both worms and mammals. Common between animals This paper begins with a striking fact: C.elegans worms, mice, and people all lose memory with age [1] and
Dublin Longevity Declaration Off to a Good Start
October 6, 2023
The Dublin Longevity Declaration, an unprecedented initiative that aims to change humanity’s perception of aging, is scooping signatures at a record pace. The need for a paradigm shift Last August, hundreds of longevity enthusiasts, from certified geroscience stars to graduate students, gathered in Dublin for the
Improving Quality and Length of Life with Stem Cells
October 5, 2023
A review article published in Stem Cell Research & Therapy has described the ways in which mesenchymal stromal cells (MSCs) are being developed to treat diseases, including age-related diseases. A lack of clinical treatments The reviewers begin their paper by discussing the most common age-related diseases.