Category: News
Rejuvenation Roundup March 2023
April 3, 2023
March marks the beginning of spring and the time for renewal, and this month, labs around the world have looked into renewing older concepts of aging and discovered potential methods
Daily Step Count, Less Mortality, Diminishing Returns
March 31, 2023
A new study using wearable accelerometers suggests that you don’t have to clock extreme numbers of steps every day to stay healthy [1]. Do you always need to hit the
Using AI to Measure Age Through the Eyes
March 30, 2023
An accepted manuscript in eLife Sciences has described eyeAge, a new clock that uses deep learning to analyze the eye in detail in order to predict chronological age and age acceleration.
Inhibiting DREAM for Enhanced DNA Damage Repair
March 29, 2023
In a new study published in Nature Structural and Molecular Biology, researchers have demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it might
Vesicles from Senescent Cells Encourage Young Stem Cells
March 28, 2023
Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not
Senescent Cells and Loose Teeth
March 27, 2023
A team of researchers has recently published a study on the effects of senescence on periodontal tissues in Aging. Connecting bones and teeth We have previously outlined a study showing
Dr. Nir Barzilai on How to Age Later
March 27, 2023
In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a
Ashley Zehnder on Harnessing Animal Genes Against Aging
March 24, 2023
Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling.
Promoting Muscle Regeneration With an Immune Factor
March 23, 2023
A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons
Journal Club March 2023 + Zoom Connection Details
March 23, 2023
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which
Long-Term Resistance Exercise Increases Autophagy
March 22, 2023
In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy Disabled autophagy was
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes,
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions
Rejuvenation Roundup March 2023
April 3, 2023
March marks the beginning of spring and the time for renewal, and this month, labs around the world have looked into renewing older concepts of aging and discovered potential methods for renewing our bodies. LEAF News Partnership Opportunities for the 5th Annual Age-Related Disease Therapeutics Summit:
Daily Step Count, Less Mortality, Diminishing Returns
March 31, 2023
A new study using wearable accelerometers suggests that you don’t have to clock extreme numbers of steps every day to stay healthy [1]. Do you always need to hit the target? A tight association between physical activity and health is widely known [2]. In fact, staying
Using AI to Measure Age Through the Eyes
March 30, 2023
An accepted manuscript in eLife Sciences has described eyeAge, a new clock that uses deep learning to analyze the eye in detail in order to predict chronological age and age acceleration. Retinal signs of aging This project was developed with the knowledge that fundus imagery, which shows
Inhibiting DREAM for Enhanced DNA Damage Repair
March 29, 2023
In a new study published in Nature Structural and Molecular Biology, researchers have demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it might be possible to alter the number of DNA mutations accumulated with age [1]. Mutations and DREAMs
Vesicles from Senescent Cells Encourage Young Stem Cells
March 28, 2023
Scientists have shown that extracellular vesicles derived from senescent stem cells can improve the proliferation, viability, and migration capacity of healthy stem cells [1]. Cell-to-cell packages Extracellular vesicles (EVs, not to be confused with electric vehicles) are tiny membrane-bound bubbles that are emitted by cells and
Senescent Cells and Loose Teeth
March 27, 2023
A team of researchers has recently published a study on the effects of senescence on periodontal tissues in Aging. Connecting bones and teeth We have previously outlined a study showing a relationship between gum disease and biomarkers of inflammation. Noting that aging itself is a risk
Dr. Nir Barzilai on How to Age Later
March 27, 2023
In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a renowned gerontologist and the director of the Institute for Aging Research at the Albert Einstein College
Ashley Zehnder on Harnessing Animal Genes Against Aging
March 24, 2023
Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling. However, this research is not purely academic anymore. A handful of bold entrepreneurs are trying to
Promoting Muscle Regeneration With an Immune Factor
March 23, 2023
A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons for the decline of regenerative abilities with aging. The first is stem cell exhaustion, the gradual
Journal Club March 2023 + Zoom Connection Details
March 23, 2023
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which looked at the effects of prolonged fasting on human macrophages and how metabolites from that fasting
Long-Term Resistance Exercise Increases Autophagy
March 22, 2023
In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy Disabled autophagy was recently acknowledged as a hallmark of aging. Indeed, boosting the ability of cells to get rid
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The Mediterranean diet, which is based on ingredients such as olive oil, vegetables, legumes, fish, and whole
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2 as part of the Kennedy pathway to synthesize two critical components of the phosopholipid membrane that
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease [1]. These diseases, representing fundamental problems with how the
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions of one of its co-chairs. Longevity is bipartisan The fight against aging must become one of