Category: News
A Fresh Examination of Epigenetic Clocks
February 17, 2022
In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks
Muscular Oxidative Capacity Predicts Mobility Decline
February 16, 2022
Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the
New Treatment for Osteoarthritis Proposed
February 15, 2022
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer,
Puerarin Shows Promise in Fighting COPD in Cells
February 14, 2022
Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption
New Partial Reprogramming Drastically Lowers Cellular Age
February 11, 2022
In a pre-print paper that has not yet been peer reviewed, a group of researchers presented a new highly efficient method of partial cellular reprogramming [1]. Young from old Our
Debunking Myths About Work Stress and Age Acceleration
February 10, 2022
A study published in Aging that studied the Northern Finland Birth Cohort of 1966 has found some interesting and counterintuitive results regarding work stress and accelerated epigenetic aging. Work stress
Researcher Offers A Critique of Geroscience
February 10, 2022
Eric Le Bourg has published a thought-provoking paper in Biogerontology that offers a critique of geroscience [1]. Geroscience, we need to talk… When people discuss the prospects of targeting the
Irina Conboy on Heterochronic Plasma at EARD2021
February 9, 2022
At Ending Age-Related Diseases 2021, Irina Conboy discussed the effects of plasma dilution and heterochronic plasma exchange and their relationship to epigenetic alterations. Script Thank you for inviting me again,
A Polyphenol-Rich Diet Reduces Age-Related Cognitive Decline
February 9, 2022
A preprint study originating from the DIRECT PLUS trial was recently released from the American Journal of Clinical Nutrition [1]. This study has been accepted into the journal but has
Senolytics for Cardiac Regeneration in Diabetics
February 9, 2022
The latest research published in Diabetes has implicated senescent cardiac stem cells as the link between diabetes and cardiovascular disease [1]. Why does diabetes increase the risk of cardiovascular disease?
Longevity Allele Slows Immune and Cardiovascular Aging
February 8, 2022
In a new study, mice transduced with a longevity-associated variant (LAV) of the BPIFB4 gene showed less immunosenescence and healthier vasculature [1]. The importance of having good genes Longevity-associated alleles
Mapping the Gene Expression of Senescent Brain Cells
February 7, 2022
As explained in a paper published in GeroScience, researchers have used spatial transcriptomic analysis to show the inflammatory nodes that are caused by brain cells undergoing senescence. What is spatial
Effective New Method of Cellular Reprogramming Proposed
February 4, 2022
Scientists have proposed a novel method of cellular reprogramming that is more predictable and effective than traditional methods [1]. Geroscience’s Holy Grail Cellular reprogramming is a hot topic in geroscience
Naked Mole Rats Age, but Not Like Other Mammals
February 3, 2022
A research paper published in Nature by Dr. Vadim Gladyshev and his team has investigated the epigenetic aging of the naked mole rat, an animal whose mortality rate does not
Higher Diet Quality Is Linked to Reduced Epigenetic Aging
February 2, 2022
A study published in the American Journal of Clinical Nutrition examined the relationship between diet quality and epigenetic aging clocks [1]. This study used data from the Framingham Heart Study
A Fresh Examination of Epigenetic Clocks
February 17, 2022
In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks work. What is a CpG site? Methylation cannot occur everywhere in the genome. The researchers explain
Muscular Oxidative Capacity Predicts Mobility Decline
February 16, 2022
Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the National Institute on Aging Intramural Research program has been conducting the Baltimore Longitudinal Study of Aging
New Treatment for Osteoarthritis Proposed
February 15, 2022
In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others
Puerarin Shows Promise in Fighting COPD in Cells
February 14, 2022
Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption of mitochondria by cells. When autophagy isn’t a good thing Mitophagy is a subset of autophagy,
New Partial Reprogramming Drastically Lowers Cellular Age
February 11, 2022
In a pre-print paper that has not yet been peer reviewed, a group of researchers presented a new highly efficient method of partial cellular reprogramming [1]. Young from old Our cells age, and old cells differ from young ones in multiple ways, including gene expression, telomere
Debunking Myths About Work Stress and Age Acceleration
February 10, 2022
A study published in Aging that studied the Northern Finland Birth Cohort of 1966 has found some interesting and counterintuitive results regarding work stress and accelerated epigenetic aging. Work stress is widely associated with premature death It is common folk wisdom that too much stress leads
Researcher Offers A Critique of Geroscience
February 10, 2022
Eric Le Bourg has published a thought-provoking paper in Biogerontology that offers a critique of geroscience [1]. Geroscience, we need to talk… When people discuss the prospects of targeting the aging processes to prevent, halt, or even reverse age-related diseases, their beliefs often fall into two
Irina Conboy on Heterochronic Plasma at EARD2021
February 9, 2022
At Ending Age-Related Diseases 2021, Irina Conboy discussed the effects of plasma dilution and heterochronic plasma exchange and their relationship to epigenetic alterations. Script Thank you for inviting me again, it’s much appreciated. This is an excellent conference series. I will start by telling you that
A Polyphenol-Rich Diet Reduces Age-Related Cognitive Decline
February 9, 2022
A preprint study originating from the DIRECT PLUS trial was recently released from the American Journal of Clinical Nutrition [1]. This study has been accepted into the journal but has not yet been peer reviewed. Duckweed for health This study focused on a plant called Mankai,
Senolytics for Cardiac Regeneration in Diabetics
February 9, 2022
The latest research published in Diabetes has implicated senescent cardiac stem cells as the link between diabetes and cardiovascular disease [1]. Why does diabetes increase the risk of cardiovascular disease? Type 2 diabetes mellitus is closely related to aging. Aging is a major risk factor for
Longevity Allele Slows Immune and Cardiovascular Aging
February 8, 2022
In a new study, mice transduced with a longevity-associated variant (LAV) of the BPIFB4 gene showed less immunosenescence and healthier vasculature [1]. The importance of having good genes Longevity-associated alleles prove that aging does not affect everyone equally. On average, centenarians and supercentenarians are more protected
Mapping the Gene Expression of Senescent Brain Cells
February 7, 2022
As explained in a paper published in GeroScience, researchers have used spatial transcriptomic analysis to show the inflammatory nodes that are caused by brain cells undergoing senescence. What is spatial transcriptomic analysis? Spatial transcription analysis isn’t a full 3D view of an entire brain. Rather, it
Effective New Method of Cellular Reprogramming Proposed
February 4, 2022
Scientists have proposed a novel method of cellular reprogramming that is more predictable and effective than traditional methods [1]. Geroscience’s Holy Grail Cellular reprogramming is a hot topic in geroscience that is being pursued by many academics and companies, including major players such as Google’s Calico
Naked Mole Rats Age, but Not Like Other Mammals
February 3, 2022
A research paper published in Nature by Dr. Vadim Gladyshev and his team has investigated the epigenetic aging of the naked mole rat, an animal whose mortality rate does not appear to increase with age. Do naked mole rats actually age? In this paper, the researchers
Higher Diet Quality Is Linked to Reduced Epigenetic Aging
February 2, 2022
A study published in the American Journal of Clinical Nutrition examined the relationship between diet quality and epigenetic aging clocks [1]. This study used data from the Framingham Heart Study Offspring Cohort. This specific study noted the Dietary Approaches to Stop Hypertension (DASH) scores, which are