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Education about aging and research is a key component of the LIfespan.io mission.

Discover Topics About Longevity

Our goal is to share evidence-based knowledge about aging and rejuvenation among the general public and cut through the misleading and confusing storm of information out there. With that in mind, we have created a range of topics covering supplements, exercise, diet, lifestyle and more for you to enjoy. These are larger articles than the news stories and are essentially a deeper dive into the science behind specific subjects.

We also have the Rejuvenation Roadmap, a curated database that tracks the many approaches and companies developing interventions against aging and their progress.

The Latest Longevity Topics

  • Low-Dose Naltrexone: Benefits and Side Effects

    Low-Dose Naltrexone: Benefits and Side Effects

    Naltrexone is a medication approved by the FDA to treat opioid addiction and alcohol dependence. This drug was developed in 1961 [1-2].  Naltrexone blocks the action of opioids at three key receptors that regulate a range of bodily […]
  • Pterostilbene: Benefits, Side Effects, and Research

    Pterostilbene: Benefits, Side Effects, and Research

    Pterostilbene is a popular supplement, especially within the longevity community. Perhaps most associated with blueberries which contain this substance, we take a look at its potential benefits. What is Pterostilbene? Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a naturally occurring polyphenol, a […]
  • Why We Age: Disabled Macroautophagy

    Why We Age: Disabled Macroautophagy

    Every human cell can be seen as a tightly run metropolis. To keep things humming, it relies on macroautophagy, a process akin to a high-tech recycling system [1]. Here’s how it works: damaged […]
  • Spermidine: Benefits, Uses, and Side Effects

    Spermidine: Benefits, Uses, and Side Effects

    Found in grapefruit, spermidine is one of the more interesting polyamines. Some research suggests that spermidine may slow down aging and promote healthy longevity. What is spermidine? Spermidine is a polyamine, […]
  • Resveratrol: Benefits, Side Effects, and Research

    Resveratrol: Benefits, Side Effects, and Research

    Resveratrol is a popular supplement especially in the longevity community. There are numerous supplement companies touting it in adverts for weight loss and longevity. But do these promises really stack up?  What is […]
  • Apigenin: Benefits And Side Effects

    Apigenin: Benefits And Side Effects

    This active ingredient in chamomile tea has traditionally been used to ease anxiety and reduce stress. There have been multiple scientific studies on this traditional use […]
  • Dietary Components That Affect Blood Pressure

    Dietary Components That Affect Blood Pressure

    While some people must take medication to reduce their blood pressure in order to preserve their healthspan and lifespan, it is usually recommended to try diet- and exercise-based approaches first. While […]

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