Tag: Clock

A recent review discusses the development of biological aging clocks, their capabilities and limitations, the discoveries they enabled, and possible future developments in this area [1]. How do we measure aging? Developments in science and technology have allowed researchers to move beyond speculation and philosophical debates about aging to study its molecular underpinnings and the...

A perspective published in Aging and Disease has recommended the use of underground laboratory space in order to remove the effects of surface radiation on biological clocks. A question of entropy The cascading failure of bodily systems, leading to the loss of organ function, sits downstream of fundamental damage to genomics and epigenomics. However, how...

A new study has used aging trajectories of various cell types to predict diseases such as Alzheimer’s and lung cancer [1]. This expands on previous research into organ-specific aging. Age is more than one number Gone are the days when aging was assumed to be happening uniformly across every tissue at once. Today, we know...

A new study links accelerated aging to early-onset solid cancers, while showing that this gap is becoming wider with each new generation [1]. Why do more young people get cancer? While life expectancy has been on the rise for decades (though it has slowed in recent years), counterintuitively, early-onset cancer is becoming more common. Cancers...

A paper in Cell Genomics has described how age-related systemic inflammation (inflammaging) is related to epigenetic aging as measured by four established clocks. Tying together two well-known aspects of aging Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into the body without the drama of an infection or obvious...

A new study reported an association between having more problematic people in close networks and increased biological aging [1]. A look into the dark side Social connection has been discussed as a factor essential for well-being, reduced epigenetic aging, and inflammatory signaling [2, 3]. However, the dark side of social connections, relationships that are toxic...