Tag: Clock

A paper in Cell Genomics has described how age-related systemic inflammation (inflammaging) is related to epigenetic aging as measured by four established clocks. Tying together two well-known aspects of aging Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into the body without the drama of an infection or obvious...

A new study reported an association between having more problematic people in close networks and increased biological aging [1]. A look into the dark side Social connection has been discussed as a factor essential for well-being, reduced epigenetic aging, and inflammatory signaling [2, 3]. However, the dark side of social connections, relationships that are toxic...

In Aging Cell, researchers have published their surprising findings that epigenetic clocks are not significantly related to most measurements of metabolic health after weight loss interventions. The utility of clocks What Are Epigenetic ClocksAn epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological...

A new study has found that professional soccer players experience a drop in their biological age after a match, as measured by biomarkers assessed with state-of-the-art methylation clocks [1]. We asked Dr. Steve Horvath, the study’s co-author, to comment. Clocks, stress, and exercise Epigenetic clocks have become extremely popular in the longevity field, both as...

Researchers have developed a transcription-based clock that estimates brain age and used it to identify potential interventions against age-related neurodegeneration. Deciding which -omic to use While neurodegeneration and brain aging are not precisely the same [1], the two are tightly linked [2]. Substantial previous work has found that directly addressing brain aging in multiple forms,...

A recent study explored the differences in the speed of organ aging. The researchers have built models that can predict the odds of diseases and mortality risk based on organ-specific proteins found in plasma [1]. Not all organs age equally Since each organ in the human body is different, the way they age also differs,...