Tag: Immune System

Publishing in Aging Cell, researchers have devised a way to delay the aging of the thymus by targeting GPR40, a key receptor in its epithelial cells. The organ that involutes The thymus trains a certain subset of immune cells, which are named T cells due to their relationship with it. As the thymus ages, its...

In a recent paper, researchers have proposed that the immune system and immune surveillance play a central role in maintaining microbial composition throughout life by suppressing microbial proliferation and that aging weakens these processes [1]. Lifelong companions Aging leads to the deterioration of the organs and systems in the human body, while also altering the...

A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for weeks, while its existence and duration in humans are to be determined [1]. The inflammation that stays Obesity is a chronic, relapsing condition linked to...

An investigation into the aging immune system identified age-related changes, including sex-dependent differences, in immune cell subpopulations and gene expression. In general, females showed greater age-related changes than males, including greater changes in autoimmune gene expression [1]. Cell-by-cell analysis Aging results in changes to the function and composition of immune cells, collectively referred to as...

A new study shows that hitting a sauna for 30 minutes causes a transient spike in the number of circulating white blood cells. The researchers suggest that this exercise-like effect might provide health benefits by improving immune surveillance [1]. How does a sauna do its trick? Robust epidemiological data has associated sauna use with health...

Arming NK and T cells with metabolite-sensing receptors enhances their ability to infiltrate tumors and improves cancer outcomes in mice in a new study [1]. How to get immune cells into the tumor? One of the central challenges in cancer immunotherapy is getting the right immune cells to the right place. Natural killer (NK) cells...