Month: April 2026

Public Longevity Group
[Mountain View, September 17, 2025] — Lifespan Research Institute (LRI) today announced the launch of the Public Longevity Group (PLG), a new initiative focused on bridging the cultural gap between scientific breakthroughs in aging and their public acceptance. To kickstart its work, PLG has opened a crowdfunding campaign to develop tools that measure and strengthen...
New part and old part
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating the human body because of the vast variety of interventions that need to be performed at multiple levels, from the molecular to the whole-body. It defines...
Sleeping at desk
A recent study found an association between longer and more frequent daytime napping and higher mortality risk. The authors suggest using napping frequency and duration as behavioral markers of increased mortality risk [1]. Common activity with a dark side Daytime napping is a relatively common activity among older adults. It is estimated that between 20%...
A new study calls for caution in using the well-known senolytic treatment of dasatinib and quercetin (D+Q), showing that it causes damage in certain regions of the brain, similar to what is observed in multiple sclerosis [1]. Stem cell senescence prevents brain repair Multiple sclerosis (MS) is a brain disorder in which the patient’s own...
Obese mouse and healthy mouse
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for weeks, while its existence and duration in humans are to be determined [1]. The inflammation that stays Obesity is a chronic, relapsing condition linked to...
Wound healing
A team of scientists has examined how younger and older mice heal from wounds and found that more robust senescent cell activation in younger animals helps them heal faster. A double-edged sword Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they...
Heart attack
A new study has found that partial reprogramming mitigates the damage of myocardial infarction in mice by helping heart muscle cells to complete division [1]. When heart cells get stuck When a heart attack (myocardial infarction, MI) kills a patch of heart muscle, the adult mammalian heart cannot replace it, since the lost contractile muscle...