Category: News

Novos image

NOVOS Plans to Launch a Nutraceutical for Aging

Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes

Chromosomes and telomere loss

New Discovery in How Stem Cells Protect Telomeres

Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality

clockwork suit

New Aging Clock May Be Most Accurate to Date

These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using

Eye

Gene Therapy Trial Successfully Improves Vision

A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully

CGI of kidneys

Kidney Progenitor Cells Derived from Urine

Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells

CD38 protein image

Reviewing CD38, a Regulator of NAD+

We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this

CGI of protein structures

AI Cracks the Protein Folding Problem

Alphabet’s subsidiary DeepMind has all but solved the problem of predicting a protein’s shape from its amino acid sequence. DeepMind’s program AlphaFold reached close to 90% average accuracy, which is

Mouse eye

Reversing Cellular Age in Mice Restores Vision

Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can

researcher working with cell culture

A New Biomaterial for Thymic Cells

New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both

Small plate of food

A Key Gene Links Diet and Longevity

A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted

Disintegrating mind

Neurological Aging and the Lifespan Limit

Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in

Novos image

NOVOS Plans to Launch a Nutraceutical for Aging

Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes and get a better picture of their health. The company is launching two new supplements: NOVOS

DNA double Helix being repaired

MYSM1 Prolongs Lifespan by Regulating DNA Repair

New research has shown that a DNA repair gene modulates lifespan in mice [1]. This may serve as a therapeutic avenue or at least open the way towards dissecting the links between DNA damage and senescence. MYSM1 is a gene that removes a molecular mark known

rat on a petri dish

Decellularized, Functional Thymus Regeneration in Mice

Recent research published in Nature Communications has regenerated a functional thymus in mice, making several other discoveries along the way [1]. A new sub-type of thymus cell emerges Although it is imperative to our immune health, the thymus is an under-studied organ that slowly disappears as

Chromosomes and telomere loss

New Discovery in How Stem Cells Protect Telomeres

Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality of cancer cells [1]. Keeping telomeres in the loop One function of telomeres is to prevent

clockwork suit

New Aging Clock May Be Most Accurate to Date

These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using deep learning, has recently been created by the Hong Kong-based company Deep Longevity. There are two

Eye

Gene Therapy Trial Successfully Improves Vision

A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully treated 37 participants suffering from Leber hereditary optic neuropathy (LHON). A landmark trial for mitochondrial gene

Aging Brain Function Partially Restored With Small Molecule

Researchers from the University of California, San Francisco have discovered that a small molecule partially restores the cognitive abilities of mice suffering from age-related memory decline [1]. A response to damage As the researchers explain, when neurons detect that something has gone wrong, either through the

CGI of kidneys

Kidney Progenitor Cells Derived from Urine

Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells The kidney is, by far, the most frequently transplanted organ. This is because donors are much

CD38 protein image

Reviewing CD38, a Regulator of NAD+

We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this decline [1]. The review focuses on one of the primary culprits of NAD+ decline, the enzyme

CGI of protein structures

AI Cracks the Protein Folding Problem

Alphabet’s subsidiary DeepMind has all but solved the problem of predicting a protein’s shape from its amino acid sequence. DeepMind’s program AlphaFold reached close to 90% average accuracy, which is comparable to experimental structural analysis. Proteins: life’s multitool Proteins are the primary tool with which organisms

Glucosamine in ball-and-stick form

Study Links Glucosamine and Chondroitin to Reduced Mortality

Glucosamine and chondroitin are commonly bundled together as a dietary supplement, and a new study suggests that taking them may significantly reduce mortality. This builds on a previous epidemiological study from earlier this year, which showed that glucosamine supplementation correlates with reduced all-cause mortality. What are

Mouse eye

Reversing Cellular Age in Mice Restores Vision

Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can be reset to become younger again using this approach and are better at repairing damaged tissue.

researcher working with cell culture

A New Biomaterial for Thymic Cells

New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both in the lab and in vivo. While the fact that everyone experiences thymic involution should make

Small plate of food

A Key Gene Links Diet and Longevity

A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted therapeutic interventions. Less is more Dietary restriction is one of the most reliable ways to increase

Disintegrating mind

Neurological Aging and the Lifespan Limit

Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in her 80s and cycling in her 100s. She claimed to have achieved such a long life