Category: News

Advanced Clock

Inflammation as a Biomarker of Mortality

In a paper published in Geroscience, researchers have developed a metric of systemic inflammation and used it to estimate mortality, finding that it performs better than epigenetic clocks. Evaluating a

Robot detective

New Senolytics from Artificial Intelligence

Recent research published in Nature Communications has used machine learning algorithms to find new compounds that can eliminate senescent cells [1]. Searching for new senolytics Senolytics are molecules that destroy

Brain Inflammation

The Inflammatory Pathway to Brain Damage

Scientists publishing in Nature have explained a key pathway that leads to immune dysfunction and neurodegeneration in aging. Feeling the STING Throughout this paper, the researchers cite other papers demonstrating

Smiling older woman

Happiness and Lifespan Are Strongly Linked

Researchers publishing in BMC Geriatrics have found that people who reported being happy were considerably more likely to live longer than people who were not. Conflicting previous research The relationship

Ginkgo Biloba

The Flavonoid Rutin May Suppress Senescent Cells

Researchers publishing in Aging Cell have documented some potential effects of rutin against senescence and cancer. Rutin is a natural compound found in several plants. Another compound to fight senescence

Flavonoid Consumption Correlates With Less Biological Aging

Researchers investigated how much the consumption of flavonoids impacts the biological age of the heart, kidney, liver, and whole body [1]. Chronological age, biological age, and diet Chronological age only refers to the number of years that have passed, but biological age refers to the lasting

Extracellular Vesicles from Stem Cells Reverse Senescence

Scientists have found that bubbles secreted by embryonic stem cells counter cellular senescence, in large part due to just two tiny snippets of RNA [1]. Helpful bubbles Extracellular vesicles (EVs) are membrane-bound tiny bubbles that are loaded with various molecular cargo, such as proteins, DNA, or

Amyloid beta plaques

Restoring Helper Cell Function to Fight Alzheimer’s

In a study published in Cell Stem Cell, researchers have investigated a way to repopulate the brain with functional cells in order to fight back against Alzheimer’s disease. A gene with a microglial function Various allelles of the apolipoprotein E (APOE) genes are well-known for their

Hip fracture

Study: Vegetarians Have Higher Risk of Hip Fracture

Studying a large British cohort, scientists have found that vegetarians have an increased risk of hip fracture compared to regular meat eaters, but pescatarians and occasional meat eaters do not [1]. Diet and brittle bones Hip fracture is one of the injuries most associated with aging.

Advanced Clock

Inflammation as a Biomarker of Mortality

In a paper published in Geroscience, researchers have developed a metric of systemic inflammation and used it to estimate mortality, finding that it performs better than epigenetic clocks. Evaluating a danger This paper begins with familiar discussions about inflammaging and epigenetic clocks, tools that use DNA

Robot detective

New Senolytics from Artificial Intelligence

Recent research published in Nature Communications has used machine learning algorithms to find new compounds that can eliminate senescent cells [1]. Searching for new senolytics Senolytics are molecules that destroy senescent cells. Only a small number of such molecules have been identified, and only two have

Gallium

Liquid Metal Nanoparticles Eradicate Colon Cancer in Mice

Scientists have combined gallium nanoparticles with immunotherapy agents to deliver a decisive blow to colon cancer tumors in mice [1]. Cancer, you are terminated Most moviegoers are familiar with the liquid metal T-1000 from the Terminator series, and everyone knows about mercury, a liquid metal that

Sweetener Packets

Artificial Sweeteners Associated with Fat, Weight Gain

A longitudinal analysis of a large cohort suggests an association between artificial sweetener intake and several markers of adiposity, such as visceral fat [1]. Safely sweet? Artificial sweeteners were invented to provide a healthier alternative to sugar and other high-calorie sweeteners, especially in the wake of

Brain Inflammation

The Inflammatory Pathway to Brain Damage

Scientists publishing in Nature have explained a key pathway that leads to immune dysfunction and neurodegeneration in aging. Feeling the STING Throughout this paper, the researchers cite other papers demonstrating a cause-and-effect relationship between initial damage and long-term effects. Perturbed mitochondria release their mitochondrial DNA (mtDNA)

Smiling older woman

Happiness and Lifespan Are Strongly Linked

Researchers publishing in BMC Geriatrics have found that people who reported being happy were considerably more likely to live longer than people who were not. Conflicting previous research The relationship between happiness and health, even controlling for other relevant factors, has been frequently confirmed and occasionally

Planking

Analysis: Isometric Exercises Are Best for Blood Pressure

In a new expansive meta-analysis comparing several types of exercise, isometric exercises, which include wall squats and planks, were linked to the biggest decrease in blood pressure [1]. Lowering the pressure As is very well-known, exercise confers numerous health benefits, including age-related benefits, and it has

Ginkgo Biloba

The Flavonoid Rutin May Suppress Senescent Cells

Researchers publishing in Aging Cell have documented some potential effects of rutin against senescence and cancer. Rutin is a natural compound found in several plants. Another compound to fight senescence In this study, the researchers place rutin among the many other natural compounds that have demonstrated

Calcium

Impaired Calcium Uptake May Impact Long-Term Inflammation

Scientists have reported in Nature Aging that impaired mitochondrial uptake of calcium ions leads to changes in inflammatory responses that resemble what happens in aging [1]. Inflammation and aging Inflammation is an essential, evolutionarily conserved process and a fundamental part of the immune response, providing immediate

Reaching for the sun

Impact of Vitamin D Supplements on Mortality Risk

In a new study published in Nutrients, researchers analyzed the results of 80 randomized clinical trials and assessed the impact of vitamin D supplementation on mortality [1]. Vitamin D plays essential roles in human health According to the CDC, 6.7% to 36.9% of Americans take vitamin

Old mouse and young mouse

Heterochronic Parabiosis Extends the Lives of Mice

For the first time, scientists have shown that letting young and old mice share blood leads to a significant lifespan extension in the old mouse [1]. Rejuvenation by young blood Since the dawn of civilization, young blood has been credited with healing and rejuvenating powers, and