Category: News
Dr. Aubrey de Grey Will Speak at the Longevity Summit Dublin
August 23, 2022
We recently caught up with Dr. Aubrey de Grey and talked to him about the upcoming Dublin Longevity Summit and how things are looking on the advocacy landscape. Hi Aubrey,
The Relationship Between Stroke and Inflammation
August 22, 2022
Publishing in Aging, a team of Chinese researchers has provided evidence showing a relationship between systemic inflammation and prognosis after a stroke. Stroke is a deadly and common affliction As
New Synthetic Molecule Alleviates Alzheimer’s in Mice
August 19, 2022
Scientists have synthesized a molecule that alleviates Alzheimer’s in a mouse model by targeting inflammation [1]. Aβ or inflammation? Two of the most prominent – and probably interconnected – symptoms
Combining Senolytic Pathways Has Synergistic Effects
August 18, 2022
A team of researchers have explained in Aging how multiple compounds that target the BCL-2 protein family are considerably more effective against senescent cells than each compound by itself [1].
Dietary Restrictions Do Not Help Cognitive Function in Mice
August 17, 2022
A new study published in Neurobiology of Aging has shown that neither caloric restriction nor intermittent fasting improve late-life cognition in genetically diverse mice, but the effect depends on genetic
Identifying Mitonuclear Genes for Longevity
August 17, 2022
Publishing in GeroScience, a team of researchers that included Nir Barzilai and Matt Kaeberlein examined genes that may affect both mitochondria and lifespan [1]. From the mitochondria to the nucleus
Rapamycin-Loaded Microneedles Reverse Hair Loss in Mice
August 16, 2022
Scientists have successfully regrown hair in a mouse model of hair loss using custom-made plastic microneedles loaded with rapamycin and epigallocatechin gallate (EGCG), an active ingredient in green tea [1].
Martin O’Dea Talks About the Longevity Summit
August 16, 2022
We recently had the opportunity to speak to Martin O’Dea about a new longevity-focused event happening in Ireland’s capital city on September 18th-20th. Martin holds an MBS and is a
Prof. Albert-László Barabási on Network Medicine
August 15, 2022
Albert-László Barabási is the Robert Gray Dodge Professor of Network Science at Northeastern University, and he also holds an appointment in the Department of Medicine at Harvard Medical School. We
Announcing the Longevity Prize
August 12, 2022
The Longevity Prize is a series of prizes designed to honor the researchers who are helping to build a future in which age-related diseases are a thing of the past.
Hypertension Is Associated with Brain Drainage Changes
August 11, 2022
Researchers publishing in Aging have found that enlarged perivascular spaces (ePVS) in the brain are correlated with vascular disorders [1]. These spaces, which are part of the brain’s glymphatic system,
An In-Depth Review of Skin Aging Genes
August 10, 2022
In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental)
Scientists Move the Boundaries of Post-Mortem Recovery
August 9, 2022
Researchers have been able to achieve substantial recovery of cellular and organismal activity in pigs that had been dead for a full hour [1]. When is it too late? Advances
Developing Nanobodies to Fight Parkinson’s Disease
August 8, 2022
A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1].
Steve Horvath on the Present and Future of Epigenetic Clocks
August 8, 2022
Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about
Dr. Aubrey de Grey Will Speak at the Longevity Summit Dublin
August 23, 2022
We recently caught up with Dr. Aubrey de Grey and talked to him about the upcoming Dublin Longevity Summit and how things are looking on the advocacy landscape. Hi Aubrey, great to see that you are the co-organizer and a keynote speaker at the Longevity Summit
The Relationship Between Stroke and Inflammation
August 22, 2022
Publishing in Aging, a team of Chinese researchers has provided evidence showing a relationship between systemic inflammation and prognosis after a stroke. Stroke is a deadly and common affliction As the researchers point out, strokes are the leading cause of death in China, with strokes caused
New Synthetic Molecule Alleviates Alzheimer’s in Mice
August 19, 2022
Scientists have synthesized a molecule that alleviates Alzheimer’s in a mouse model by targeting inflammation [1]. Aβ or inflammation? Two of the most prominent – and probably interconnected – symptoms of Alzheimer’s disease are the accumulation of amyloid beta (Aβ) and chronic neuroinflammation. While the first
Combining Senolytic Pathways Has Synergistic Effects
August 18, 2022
A team of researchers have explained in Aging how multiple compounds that target the BCL-2 protein family are considerably more effective against senescent cells than each compound by itself [1]. The limitations of existing senolytics The researchers begin their paper with a familiar discussion of senescent
Dietary Restrictions Do Not Help Cognitive Function in Mice
August 17, 2022
A new study published in Neurobiology of Aging has shown that neither caloric restriction nor intermittent fasting improve late-life cognition in genetically diverse mice, but the effect depends on genetic composition [1]. Eat less, think better? Dietary interventions are known to have potential to extend lifespan
Identifying Mitonuclear Genes for Longevity
August 17, 2022
Publishing in GeroScience, a team of researchers that included Nir Barzilai and Matt Kaeberlein examined genes that may affect both mitochondria and lifespan [1]. From the mitochondria to the nucleus Over time, evolution has moved mitochondrial DNA from the individual mitochondria to the nucleus, where they
Rapamycin-Loaded Microneedles Reverse Hair Loss in Mice
August 16, 2022
Scientists have successfully regrown hair in a mouse model of hair loss using custom-made plastic microneedles loaded with rapamycin and epigallocatechin gallate (EGCG), an active ingredient in green tea [1]. A hairy problem While not life-threatening or debilitating, age-related hair loss (senescent alopecia) is one of
Martin O’Dea Talks About the Longevity Summit
August 16, 2022
We recently had the opportunity to speak to Martin O’Dea about a new longevity-focused event happening in Ireland’s capital city on September 18th-20th. Martin holds an MBS and is a business lecturer at Dublin Business School in Dublin, Ireland. He is also the author of Beyond
Prof. Albert-László Barabási on Network Medicine
August 15, 2022
Albert-László Barabási is the Robert Gray Dodge Professor of Network Science at Northeastern University, and he also holds an appointment in the Department of Medicine at Harvard Medical School. We talked about a revolutionary ‘network medicine’ approach that can greatly enhance our ability to understand biological
Announcing the Longevity Prize
August 12, 2022
The Longevity Prize is a series of prizes designed to honor the researchers who are helping to build a future in which age-related diseases are a thing of the past. This new initiative aims to accelerate progress in the rejuvenation biotechnology field and encourage innovation. While
Hypertension Is Associated with Brain Drainage Changes
August 11, 2022
Researchers publishing in Aging have found that enlarged perivascular spaces (ePVS) in the brain are correlated with vascular disorders [1]. These spaces, which are part of the brain’s glymphatic system, allow for the drainage of potentially dangerous metabolites such as beta amyloid [2]. A known biomarker
An In-Depth Review of Skin Aging Genes
August 10, 2022
In a new systematic review published in Scientific Reports, multiple genes driving skin aging were identified [1]. The authors start by explaining the intrinsic (genetic and chronological) and extrinsic (environmental) factors that drive skin aging. While the environmental factors that affect the rate of skin aging,
Scientists Move the Boundaries of Post-Mortem Recovery
August 9, 2022
Researchers have been able to achieve substantial recovery of cellular and organismal activity in pigs that had been dead for a full hour [1]. When is it too late? Advances in resuscitation have already moved the boundaries of life and death, making it possible to revive
Developing Nanobodies to Fight Parkinson’s Disease
August 8, 2022
A team of researchers publishing in Nature Communications has described nanobodies that can destroy the α-synuclein aggregates that characterize Lewy bodies, which are associated with dementia and Parkinson’s disease [1]. What are nanobodies? Traditional antibody therapies, while promising in some studies, are too large to enter
Steve Horvath on the Present and Future of Epigenetic Clocks
August 8, 2022
Dr. Steve Horvath hardly needs an introduction, so we will be brief: he is the inventor of the epigenetic clock and, currently, principal investigator at Altos Labs. We talked about the recent developments in this immensely important field, including pan-mammalian clocks, two-species clocks, and single-cell clocks,