Category: News

David Barzilai

An Anonymous Longevity Enthusiast Unmasks Himself

A prolific anonymous poster who became popular in the longevity community has revealed his identity, and other longevity luminaries have chimed in. The anonym Anonymity is seldom practiced in the

Chromatin

Pushing Forward on Understanding Cellular Decline

Researchers publishing in Nature Aging have investigated one of the core biological reasons behind the decline of stem cells’ ability to proliferate. Heterochromatin and euchromatin The genetic component of cells

Dietary choices

Promoting Health and Longevity Through Diet

A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, live healthier and longer

Rat looking at camera

Targeting Metabolism to Protect Against Stroke

Japanese researchers publishing in Aging have described how improving the AMPK metabolic pathway improves outcomes in a rat model of stroke. Targeting metabolism directly This paper begins with a look

Gift giving

Cells Regularly Donate Mitochondria to One Another

In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies.

Extra Virgin Olive Oil

Olive Oil Fights Cognitive Decline in Clinical Trials

In a recent review published in Frontiers in Nutrition, the researchers reviewed studies linking olive oil consumption to cognitive performance [1]. Dietary interventions to improve cognition As life expectancy rises,

Elderly Alcohol

Epigenetic Age Accelerated By Drinking Alcohol

A new study has found that higher levels of long-term alcohol consumption are associated with a larger gap between the person’s biological and chronological age, but not in the young

Ancient clock

Predicting Future Frailty with an Epigenetic Clock

An accepted manuscript in the Journals of Gerontology has described how a third-generation epigenetic clock is a predictor  of future frailty. Are epigenetic and physiological metrics connected? This paper begins

Basal cell carcinoma

Skin Collagen Loss Makes It Easier For Cancer To Grow

A new paper published in Nature has described how the aging extracellular matrix makes it easier for cancer to grow. When cancer is skin deep Under normal circumstances, we lose and regain skin cells constantly. Old skin flakes away, and stem cells constantly divide and differentiate

David Barzilai

An Anonymous Longevity Enthusiast Unmasks Himself

A prolific anonymous poster who became popular in the longevity community has revealed his identity, and other longevity luminaries have chimed in. The anonym Anonymity is seldom practiced in the longevity community. Everyone knows everyone, and on social media, most people use their real names rather

Chromatin

Pushing Forward on Understanding Cellular Decline

Researchers publishing in Nature Aging have investigated one of the core biological reasons behind the decline of stem cells’ ability to proliferate. Heterochromatin and euchromatin The genetic component of cells is comprised of two main parts: heterochromatin and euchromatin. Heterochromatin is largely silent, as it is

Meat versus plants

Plant-Based Alternatives Are Associated With Less Disease

A new meta-analysis has found that in many cases, switching from an animal product to a plant-based alternative is associated with less cardiovascular, diabetes, and all-cause mortality risk [1]. Supplant with plant? Whether a completely or mostly plant-based diet is good for you has been the

Brain COVID

Senolytics May Work Against Long COVID in the Brain

A new publication in Nature Aging has used organoids and model mice to discover that senolytics may be effective treatments for neurodegeneration caused by long COVID. A link between COVID-19 and cellular senescence Post-acute infection syndromes (PAISes) are caused by a variety of viral and bacterial

Dietary choices

Promoting Health and Longevity Through Diet

A review published in the Journal of Internal Medicine summarized current knowledge on the impact of dietary factors on chronic diseases and longevity [1]. Restrict calories, live healthier and longer The choice of what someone eats obviously has a profound impact on that person’s health, but

Fang feng

Saposhnikovia Root Extract Improves Tendon Repair

A new study has identified a molecule found in Saposhnikovia root as a potent mediator of tendon regeneration in rats. The results were also replicated in human cells [1]. Aging does not spare tendons Like with many tissues, the health of tendons, which are central to

Rat looking at camera

Targeting Metabolism to Protect Against Stroke

Japanese researchers publishing in Aging have described how improving the AMPK metabolic pathway improves outcomes in a rat model of stroke. Targeting metabolism directly This paper begins with a look back at previous research on the focus of this study, 5′-adenosine monophosphate-activated protein kinase (AMPK). This

Food choices

Mediterranean, Keto, and Plant-Based Diets Vs. Cancer

A new review summarizes what we know about the Mediterranean, keto, and plant-based diets and their effects on cancer risk and progression [1]. Diet matters Since the War on Cancer began in the early 1970s, science has made giant strides in understanding and treating cancer. However,

Gift giving

Cells Regularly Donate Mitochondria to One Another

In a review published in Nature, researchers have explained how and why cells transfer mitochondria to one another, proposing that this transfer allows organisms to be more resilient against energy deficiencies. A relatively recent discovery It was not until 2006 when a team of researchers realized that

Extra Virgin Olive Oil

Olive Oil Fights Cognitive Decline in Clinical Trials

In a recent review published in Frontiers in Nutrition, the researchers reviewed studies linking olive oil consumption to cognitive performance [1]. Dietary interventions to improve cognition As life expectancy rises, there is an increasing number of elderly people, many of whom struggle with cognitive decline. However,

Older man exercising

Lifestyle Interventions Against Cellular Senescence

A new review summarizes our knowledge about lifestyle interventions, such as exercise, healthy diet, and good sleep, that can possibly reduce cellular senescence [1]. What do we do with a senescent cell? Senescent cells play a complex role. In some contexts, such as early organismal development

Tweaking the Growth of Stem Cells for Better Therapies

Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, potentially paving the way to a new system of therapies. When signaling is critical Many of the effects of

Elderly Alcohol

Epigenetic Age Accelerated By Drinking Alcohol

A new study has found that higher levels of long-term alcohol consumption are associated with a larger gap between the person’s biological and chronological age, but not in the young [1]. Don’t drink and age It is common knowledge that excessive drinking can be quite harmful

Ancient clock

Predicting Future Frailty with an Epigenetic Clock

An accepted manuscript in the Journals of Gerontology has described how a third-generation epigenetic clock is a predictor  of future frailty. Are epigenetic and physiological metrics connected? This paper begins with an examination of two different methods of measuring aging processes. The first is the well-known