Category: News

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club May 2023

The Journal Club returns on Tuesday May 23rd at 12:00 Eastern with your host, Dr. Oliver Medvedik. This month, we are taking a look at a recent paper where researchers

Disease analysis

Building Artificial Organoids to Study Diseases

In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and

Heartbeat

Destroying ‘Zombie’ Cells for Cardiovascular Health

Researchers have demonstrated that two senolytic drugs might improve how the heart repairs itself by destroying senescent cells [1]. These harmful cells are associated with many age-related diseases, including cardiovascular

Conboy Interview

Irina Conboy on Academic Publishing

Today, we are talking with Dr. Irina Conboy, Editor-in-Chief of the journal Rejuvenation Research about impact and other aspects of journal publishing. This journal is an important academic publication for

Gorbunova Interview

Vera Gorbunova on Long-Lived Species

  Dr. Vera Gorbunova is a famous geroscientist who, for the last several years, has worked mostly on uncovering the amazing biological mechanisms that are responsible for the enviable longevity

AI drug discovery

Using Machine Learning to Find Senolytics

Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective

AI answers healthcare questions.

AI Better Than Humans At Healthcare Questions

Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to

Outlive

Dr. Peter Attia on How to Outlive

Peter Attia, M.D., popular host of The Drive, has nearly a million followers across his social media platforms. In his first book, OUTLIVE The Science and Art of Longevity, he

Rejuvenation Roundup April

Rejuvenation Roundup April 2023

As the second month of spring, April is often associated with rebirth, and we’ve added rejuvenation to the mix with cryptocurrency donation initiatives, biotechnology company progress, and plenty of science.

Astrocyte

Targeting Age-Related Metabolic Shifts in the Brain

Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia To perform various maintenance and protective tasks, the brain contains a large population of microglia alongside its neurons.

Kelsey Moody

Kelsey Moody on Supporting New Researchers with Ichor

Today, we are speaking to Ichor Life Sciences CEO Dr. Kelsey Moody about the doctoral program that the company operates and how the company is supporting the next generation of scientists. Ichor Life Sciences is a biotechnology company that develops and manufactures new medicines for people

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club May 2023

The Journal Club returns on Tuesday May 23rd at 12:00 Eastern with your host, Dr. Oliver Medvedik. This month, we are taking a look at a recent paper where researchers have engineered cells to age slower using synthetic biology [1]. Synthetic biology is an area of

Disease analysis

Building Artificial Organoids to Study Diseases

In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and develop treatments. Different sources for different conditions This review includes both human embryonic stem cells (hESCs),

Heartbeat

Destroying ‘Zombie’ Cells for Cardiovascular Health

Researchers have demonstrated that two senolytic drugs might improve how the heart repairs itself by destroying senescent cells [1]. These harmful cells are associated with many age-related diseases, including cardiovascular disease. Zombie cells that refuse to die As we age, our bodies accumulate senescent cells, often

Blank credentials

Protecting Mass-Produced Stem Cells from the Immune System

Researchers publishing in Nature Biotechnology have demonstrated a method of protecting mass-produced stem cells from the immune system, with strongly positive results in two different animal models. Fake ID for the immune system While it would be ideal to create stem cells from each person’s existing

Conboy Interview

Irina Conboy on Academic Publishing

Today, we are talking with Dr. Irina Conboy, Editor-in-Chief of the journal Rejuvenation Research about impact and other aspects of journal publishing. This journal is an important academic publication for our field and publishes many papers focused on aging and rejuvenation research. Hi, Irina, and thanks

Gorbunova Interview

Vera Gorbunova on Long-Lived Species

  Dr. Vera Gorbunova is a famous geroscientist who, for the last several years, has worked mostly on uncovering the amazing biological mechanisms that are responsible for the enviable longevity and resilience of long-lived species such as the naked mole rat. We talked about those feats

Treadmill mouse

Gene Therapy Ameliorates Sarcopenia in Old Mice

A paper published in Aging has detailed how gene therapy has been used to treat sarcopenia in wild-type mice, and the results are positive. A lack of effective treatments As expected with papers of this kind, the researchers begin by discussing frailty and sarcopenia, the age-related

AI drug discovery

Using Machine Learning to Find Senolytics

Research published today in Nature Aging has described a machine learning algorithm that finds senescent cell-removing drugs (senolytics) and compared the algorithm’s discoveries to existing compounds. A quest for effective therapeutics After covering familiar territory regarding senescent cells, this paper begins with a discussion of existing

AI answers healthcare questions.

AI Better Than Humans At Healthcare Questions

Scientists have compared doctor-written and chatbot-generated responses to healthcare-related questions, and the results don’t look good for Team Human [1]. Ask your doctor? Access to healthcare has been linked to longer lifespan, and good healthcare often starts with a good initial consultation. A group of researchers,

Handful of medication

Certain Medications Appear to Improve Aging Biomarkers

A twin study published in GeroScience has yielded results suggesting that calcium channel blockers, drugs that are commonly used to treat hypertension and other diseases, slow down epigenetic aging and may lengthen healthy lifespan. A wide field The researchers begin this paper by noting that over

Flavonoids

Flavonols, Especially Quercetin, Linked to Less Frailty

In a new prospective cohort study, a higher intake of flavonols, and quercetin in particular, was linked to a significant decrease in the risk of frailty [1]. Flavonoids: not just flavor Flavonoids are a class of polyphenolic compounds that include flavanols, flavonols, flavones, anthocyanins, and some

Outlive

Dr. Peter Attia on How to Outlive

Peter Attia, M.D., popular host of The Drive, has nearly a million followers across his social media platforms. In his first book, OUTLIVE The Science and Art of Longevity, he summarizes much of the evidence and wisdom that he has delivered to his audience over the

Rejuvenation Roundup April

Rejuvenation Roundup April 2023

As the second month of spring, April is often associated with rebirth, and we’ve added rejuvenation to the mix with cryptocurrency donation initiatives, biotechnology company progress, and plenty of science. LEAF News A Busy Spring for Rejuvenation Research and Advocacy: lifespan.io’s birthday was in April, and