Category: News
An Opportunity to Support Aging Research with Gitcoin
April 28, 2023
We have two scientific research projects in the new Gitcoin fundraising round. Help us to combat Alzheimer’s disease or improve how clinical trials are conducted today! An alternative way to
Netrin-1 Rescues Blood Stem Cells in Mice
April 28, 2023
Scientists have discovered that the protein Netrin-1 alleviates the age-related decline in hematopoietic stem cell function in mice, enhancing HSC transplantation and protecting these mice from the harmful effects of
Hair Pigment Stem Cells May Work Differently
April 27, 2023
Researchers publishing in Nature have made the surprising discovery that pigmentation cells (melanocytes) can naturally transition back into the stem cell state in a process called dedifferentiation. A kinship with
Zuzalu: The Experimental Pop-Up City With a Longevity Focus
April 27, 2023
The decentralized autonomous organization VitaDAO is supporting longevity realated initiatives at Zuzalu, a pop-up mini-city event in Montenegro, which aims to create a unique jurisdiction for medical innovation within a
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a
Simply Being Overweight May Not Be Harmful in Aging
April 26, 2023
According to a new large-scale populational study, being overweight is not associated with either significant risks or benefits between the ages of 45 and 85. Obesity, however, is a clear
Reprogramming Fibroblasts in Vivo for Heart Repair
April 25, 2023
Scientists from Duke University have found a way to make adult fibroblasts differentiate into cardiomyocytes, which might help develop better heart attack treatments [1]. The imperfect repair Myocardial infarction, or
Examining Cellular Stemness as a Tissue Attribute
April 24, 2023
In a preprint paper published on bioRxiv, researchers including João Pedro de Magalhães have gotten a glimpse at how stemness declines across tissues with aging. Using AI to get a
Increased Energy Efficiency Might Drive Weight Regain
April 24, 2023
Scientists have discovered that formerly obese mice that became leaner have greatly improved energy efficiency, which might be preventing their complete return to normal weight [1]. Why is it so
Sleep Quality and Duration Associated with Stroke
April 21, 2023
Showing yet again that sleep is a serious matter, scientists have reported that short sleep duration, snoring, and long naps are linked to a significantly elevated risk of acute stroke
Uncovering a Predictive Biomarker for Alzheimer’s
April 20, 2023
Researchers publishing in Alzheimer’s and Dementia have published a correlation between the Alzheimer’s-linked protein tau and another protein, bisecting N-acetylglucosamine (GlcNAc), which suggests its usefulness as a biomarker. The need
Journal Club April 2023
April 20, 2023
In the Journal Club this month, we will be exploring a new study published in Nature Structural and Molecular Biology, where researchers demonstrated that by manipulating the DREAM protein complex,
Case Reports of Sclerotic Fibrosis in the Heart
April 19, 2023
A pair of case reports published in Heliyon have shed more light on the connection between systemic sclerosis and fatal heart failure, highlighting a need for early diagnosis and treatment.
Amyloid-β Clearance by the Liver Might Help with Alzheimer’s
April 19, 2023
Chinese scientists have found that the liver removes amyloid-β from circulation in mice, which also decreases its levels in the brain. The age-related impairment of this process might offer a
Rapamycin Rescues Age-Impaired Blood Flow in Mice
April 18, 2023
Scientists have concluded that rapamycin treatment started in early mid-life can prevent age-related blood flow impairment in the hindlimbs of wild-type, atherosclerotic, and Alzheimer’s model mice [1]. PAD and aging
An Opportunity to Support Aging Research with Gitcoin
April 28, 2023
We have two scientific research projects in the new Gitcoin fundraising round. Help us to combat Alzheimer’s disease or improve how clinical trials are conducted today! An alternative way to fund science Gitcoin is a decentralized science (DeSci) platform that utilizes blockchain technology to support the
Netrin-1 Rescues Blood Stem Cells in Mice
April 28, 2023
Scientists have discovered that the protein Netrin-1 alleviates the age-related decline in hematopoietic stem cell function in mice, enhancing HSC transplantation and protecting these mice from the harmful effects of chemotherapy [1]. (Not) a niche problem Declining stem cell function (stem cell exhaustion) is linked to
Hair Pigment Stem Cells May Work Differently
April 27, 2023
Researchers publishing in Nature have made the surprising discovery that pigmentation cells (melanocytes) can naturally transition back into the stem cell state in a process called dedifferentiation. A kinship with hair follicle cells These researchers begin their study by discussing stem cells and their proliferation. In
Zuzalu: The Experimental Pop-Up City With a Longevity Focus
April 27, 2023
The decentralized autonomous organization VitaDAO is supporting longevity realated initiatives at Zuzalu, a pop-up mini-city event in Montenegro, which aims to create a unique jurisdiction for medical innovation within a more effective regulatory framework. A platform for longevity events and workshops VitaDAO is hosting unique, longevity-oriented
What AI Technology Is Doing for Longevity Now
April 26, 2023
In March 2023, MIT Technology Review revealed that Sam Altman, the CEO of OpenAI (ChatGPT), was the mystery investor behind the $180 million investment into stealth startup Retro Biosciences, a biotech company with the ambition of “adding 10 years to the human lifespan.” This investment marks
Simply Being Overweight May Not Be Harmful in Aging
April 26, 2023
According to a new large-scale populational study, being overweight is not associated with either significant risks or benefits between the ages of 45 and 85. Obesity, however, is a clear risk factor [1]. BMI plus fat mass index While obesity is widely recognized as a life-long
Reprogramming Fibroblasts in Vivo for Heart Repair
April 25, 2023
Scientists from Duke University have found a way to make adult fibroblasts differentiate into cardiomyocytes, which might help develop better heart attack treatments [1]. The imperfect repair Myocardial infarction, or heart attack, is a leading cause of death and disability. It happens when the blood flow
Examining Cellular Stemness as a Tissue Attribute
April 24, 2023
In a preprint paper published on bioRxiv, researchers including João Pedro de Magalhães have gotten a glimpse at how stemness declines across tissues with aging. Using AI to get a grasp on stemness As expected, this paper begins with a discussion of stem cell exhaustion and
Increased Energy Efficiency Might Drive Weight Regain
April 24, 2023
Scientists have discovered that formerly obese mice that became leaner have greatly improved energy efficiency, which might be preventing their complete return to normal weight [1]. Why is it so hard to lose the last few pounds? People attempting to lose weight often feel like their
Sleep Quality and Duration Associated with Stroke
April 21, 2023
Showing yet again that sleep is a serious matter, scientists have reported that short sleep duration, snoring, and long naps are linked to a significantly elevated risk of acute stroke [1]. Debilitating and deadly Stroke, an acute condition in which the blood supply to a part
Uncovering a Predictive Biomarker for Alzheimer’s
April 20, 2023
Researchers publishing in Alzheimer’s and Dementia have published a correlation between the Alzheimer’s-linked protein tau and another protein, bisecting N-acetylglucosamine (GlcNAc), which suggests its usefulness as a biomarker. The need for early prediction This paper begins with a note that to be effective, Alzheimer’s treatment must
Journal Club April 2023
April 20, 2023
In the Journal Club this month, we will be exploring a new study published in Nature Structural and Molecular Biology, where researchers demonstrated that by manipulating the DREAM protein complex, a major regulator of DNA damage response, it may be possible to reduce the number of
Case Reports of Sclerotic Fibrosis in the Heart
April 19, 2023
A pair of case reports published in Heliyon have shed more light on the connection between systemic sclerosis and fatal heart failure, highlighting a need for early diagnosis and treatment. A systemic autoimmune disease Systemic sclerosis was once known as scleroderma, as the most visible signs
Amyloid-β Clearance by the Liver Might Help with Alzheimer’s
April 19, 2023
Chinese scientists have found that the liver removes amyloid-β from circulation in mice, which also decreases its levels in the brain. The age-related impairment of this process might offer a new clue for fighting Alzheimer’s disease [1]. The janitor of the body Despite the flop-laden history
Rapamycin Rescues Age-Impaired Blood Flow in Mice
April 18, 2023
Scientists have concluded that rapamycin treatment started in early mid-life can prevent age-related blood flow impairment in the hindlimbs of wild-type, atherosclerotic, and Alzheimer’s model mice [1]. PAD and aging Peripheral artery disease (PAD) is defined as reduced blood flow to the lower limbs. Age is