Category: News
Vitalik Buterin Exclusive Interview: Longevity, AI and More
May 30, 2023
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Lai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a “pop-up city”
Centenarians Have Slightly Different Gut Ecologies
May 29, 2023
Researchers publishing in Nature Microbiology have determined that the viruses populating the intestines of centenarians are slightly different from those of the merely old. Viruses for bacteria, not people We
Hypoxia Extends Median Lifespan in Fast-Aging Mice by 50%
May 26, 2023
Scientists have found that continuous oxygen restriction drastically extends the lifespan of progeroid mice, but the effect’s mechanism remains a mystery [1]. Can less oxygen be better? Hypoxia is a
Discovering Why Adrenal Cancer Is More Dangerous for Women
May 25, 2023
A paper published today in Nature Aging has explained a relationship between cellular senescence, cancer of the adrenal glands, and sex differences. A closer look at age-related cancer Over 90%
Using AI to Discover New Rapamycin-Like Molecules
May 24, 2023
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is
How Your Funding Has Helped Mitochondrial Research
May 24, 2023
Financed by Lifespan.io’s crowdfunding efforts, SENS Research Foundation has engaged in fruitful research into ways of dealing with mitochondrial dysfunction, the gradual loss of function of our cells’ power plants.
Zuzalu Talks Longevity: Highlights from the Conference
May 23, 2023
Lifespan.io president Keith Comito presenting in Zuzalu. Photo: Arkadi Mazin While the format of this conference was rather conventional, the venue was anything but. It was held in Zuzalu, which
Summer Is Coming, and We Have Been Working Hard
May 23, 2023
For those of us in the Northern Hemisphere, spring is fast approaching summer, and warmer weather is on the way. Spring is a time of rejuvenation, exactly what our organization
A New Tool for Editing Mitochondrial DNA
May 22, 2023
Researchers publishing in Nature Biotechnology have developed a novel method of editing mitochondrial DNA, which cannot be accomplished with nuclear DNA tools. Where CRISPR doesn’t work While CRISPR is the
Rare Gene Variant Appears to Protect Against Alzheimer’s
May 19, 2023
Scientists studying people with autosomal dominant Alzheimer’s disease have found a genetic variant that is associated with decades of stalled onset [1]. The predictable Alzheimer’s Scientists still do not know
A Senolytic Drug May Already Be in the Clinic
May 18, 2023
Researchers publishing in Aging have investigated zoledronic acid, a drug already used to protect bones and fight osteoporosis, for its activity against cellular senescence. An approved drug with established effects
Targeting Age-Related Metabolic Shifts in the Brain
May 17, 2023
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia To perform
Kelsey Moody on Supporting New Researchers with Ichor
May 16, 2023
Today, we are speaking to Ichor Life Sciences CEO Dr. Kelsey Moody about the doctoral program that the company operates and how the company is supporting the next generation of
Journal Club May 2023
May 16, 2023
The Journal Club returns on Tuesday May 23rd at 12:00 Eastern with your host, Dr. Oliver Medvedik. This month, we are taking a look at a recent paper where researchers
Building Artificial Organoids to Study Diseases
May 15, 2023
In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and
Vitalik Buterin Exclusive Interview: Longevity, AI and More
May 30, 2023
Vitalik Buterin holding Zuzu, the puppy rescued by people of Zuzalu. Photo: Michelle Lai Don’t try finding Zuzalu on a map; it doesn’t exist anymore. It was a “pop-up city” conceived by the tech entrepreneur Vitalik Buterin, creator of Ethereum, and a group of like-minded people
Centenarians Have Slightly Different Gut Ecologies
May 29, 2023
Researchers publishing in Nature Microbiology have determined that the viruses populating the intestines of centenarians are slightly different from those of the merely old. Viruses for bacteria, not people We have written previously about a study showing that centenarians have youthful bacterial gut compositions (enterotypes) similar
Hypoxia Extends Median Lifespan in Fast-Aging Mice by 50%
May 26, 2023
Scientists have found that continuous oxygen restriction drastically extends the lifespan of progeroid mice, but the effect’s mechanism remains a mystery [1]. Can less oxygen be better? Hypoxia is a condition in which an organism or an organ in the body does not receive enough oxygen.
Discovering Why Adrenal Cancer Is More Dangerous for Women
May 25, 2023
A paper published today in Nature Aging has explained a relationship between cellular senescence, cancer of the adrenal glands, and sex differences. A closer look at age-related cancer Over 90% of cancer diagnoses are made in people over a half century old [1]. This is not
Using AI to Discover New Rapamycin-Like Molecules
May 24, 2023
In a recent paper published in International Journal of Medical Sciences, researchers have described how they used artificial intelligence and machine learning tools to find mTOR-inhibiting molecules [1]. mTOR is a common target for lifespan extension interventions The mechanistic target of rapamycin (mTOR) is a well-known
How Your Funding Has Helped Mitochondrial Research
May 24, 2023
Financed by Lifespan.io’s crowdfunding efforts, SENS Research Foundation has engaged in fruitful research into ways of dealing with mitochondrial dysfunction, the gradual loss of function of our cells’ power plants. Here, the organization reports its successes in handling this aspect of aging. The cellular machinery and
Zuzalu Talks Longevity: Highlights from the Conference
May 23, 2023
Lifespan.io president Keith Comito presenting in Zuzalu. Photo: Arkadi Mazin While the format of this conference was rather conventional, the venue was anything but. It was held in Zuzalu, which can’t be found on any map. Zuzalu is a unique “pop-up city” conceived by the tech
Summer Is Coming, and We Have Been Working Hard
May 23, 2023
For those of us in the Northern Hemisphere, spring is fast approaching summer, and warmer weather is on the way. Spring is a time of rejuvenation, exactly what our organization is striving to support in the fight against age-related diseases. To that end, we have been
A New Tool for Editing Mitochondrial DNA
May 22, 2023
Researchers publishing in Nature Biotechnology have developed a novel method of editing mitochondrial DNA, which cannot be accomplished with nuclear DNA tools. Where CRISPR doesn’t work While CRISPR is the established, go-to method for genetic modification in the nucleus, it doesn’t work in the mitochondria. CRISPR
Rare Gene Variant Appears to Protect Against Alzheimer’s
May 19, 2023
Scientists studying people with autosomal dominant Alzheimer’s disease have found a genetic variant that is associated with decades of stalled onset [1]. The predictable Alzheimer’s Scientists still do not know what causes most cases of Alzheimer’s, although certain genetic variants (most notably APOE4) have been shown
A Senolytic Drug May Already Be in the Clinic
May 18, 2023
Researchers publishing in Aging have investigated zoledronic acid, a drug already used to protect bones and fight osteoporosis, for its activity against cellular senescence. An approved drug with established effects Zoledronate has already been approved by the FDA for clinical use, as it has been prescribed
Targeting Age-Related Metabolic Shifts in the Brain
May 17, 2023
Publishing in Aging, a team of Chilean researchers has described a relationship between gene shifts in the brain and neurons not getting the energy they need. Greedy glia To perform various maintenance and protective tasks, the brain contains a large population of microglia alongside its neurons.
Kelsey Moody on Supporting New Researchers with Ichor
May 16, 2023
Today, we are speaking to Ichor Life Sciences CEO Dr. Kelsey Moody about the doctoral program that the company operates and how the company is supporting the next generation of scientists. Ichor Life Sciences is a biotechnology company that develops and manufactures new medicines for people
Journal Club May 2023
May 16, 2023
The Journal Club returns on Tuesday May 23rd at 12:00 Eastern with your host, Dr. Oliver Medvedik. This month, we are taking a look at a recent paper where researchers have engineered cells to age slower using synthetic biology [1]. Synthetic biology is an area of
Building Artificial Organoids to Study Diseases
May 15, 2023
In an open-access paper published in Cell Stem Cell this month, researchers have explained how organoids derived from human pluripotent stem cells (hPSCs) are being used to analyze diseases and develop treatments. Different sources for different conditions This review includes both human embryonic stem cells (hESCs),