Category: News

Vadim Gladyshev

Vadim Gladyshev on the Fundamentals of Aging

Vadim Gladyshev is a Professor of Medicine at Brigham and Women’s Hospital and Harvard Medical School, and he is one of the most prominent figures in geroscience today. We discussed

Old politician

Politicians Live Longer Than Most People

By analyzing historical data, scientists have shown that politicians, an example of an elite group, have enjoyed longer than average life expectancy since about 1950 [1]. The elite lives longer

Rejuvenation Roundup June

Rejuvenation Roundup June 2022

As rejuvenation biotechnology begins to take root, more and more biotech companies are joining the fight against aging. Here’s what’s happened in research, development, investment, and advocacy last month. LEAF

Older people running

Metformin Is Linked to Weaker Exercise Improvements

A study published in Obesity suggests that metformin may decrease the gains in cardiorespiratory performance brought on by exercise. The world’s most common diabetes drug Metabolic syndrome, which is represented

DNA Details

Longevity Through Altering Essential Gene Expression

In a new study published in GeroScience, researchers have shown that it is possible to significantly increase yeast lifespan by overexpressing genes highly conserved across various species [1]. Survival and

Cocoa

Cocoa Extract Reduces Cardiovascular Mortality

A large-scale, randomized, controlled trial has found that in aging adults, cocoa extract does not affect the prevalence of adverse cardiovascular events but decreases their lethality [1]. Rich in flavanols

Elderly eating healthy

The Relationship Between Diet and Senescence

An extremely comprehensive review published in Food Science & Biotechnology has summarized the current state of research regarding cellular senescence and basic dietary components. An aging-focused outlook The researchers begin

Strong mouse

Stem Cells for Fighting Sarcopenia

In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple

Fruits and vegetables

Fruits and Vegetables Linked to Fewer Cognitive Disorders

A meta-analysis published in Frontiers in Nutrition has found that intake of fruits and vegetables is negatively correlated with cognitive decline in older adults. A study of studies Sixteen different studies were used for this meta-analysis, and not all of them measured fruit and vegetable comsuption

Vadim Gladyshev

Vadim Gladyshev on the Fundamentals of Aging

Vadim Gladyshev is a Professor of Medicine at Brigham and Women’s Hospital and Harvard Medical School, and he is one of the most prominent figures in geroscience today. We discussed various competing hypotheses on the nature of aging, the lack of the unified theory of aging

Vascular brain

Metformin, Rapamycin, NMN, and Vascular Cognitive Impairment

A study published in Frontiers in Neurology has detailed how three well-known longevity-associated compounds affect vascular cognitive impairment (VCI) in a rat model. A rat model of a common human disease In bilateral common carotid artery occlusion (BCCAO), the arteries of rats are sutured to reduce

Astrocyte

Rejuvenating the Brain with Transplanted Astrocytes

A new study published in Stem Cell Research and Therapy has shown that rejuvenating the astrocyte niche in the aged brains of mice leads to improved nervous system function at both the cellular and organismal levels [1]. A glia-centric approach In brain aging, neurons are quite

Old politician

Politicians Live Longer Than Most People

By analyzing historical data, scientists have shown that politicians, an example of an elite group, have enjoyed longer than average life expectancy since about 1950 [1]. The elite lives longer Historical trends in health and mortality can teach us a lot about the present. It is

Collin_Ewald

Extracellular Matrix in Aging with Professor Collin Ewald

Dr. Collin Ewald is a molecular biologist and a professor at the Swiss Federal Institute of Technology in Zürich (ETH). At ETH, Collin leads the Laboratory of Extracellular Matrix (ECM) Regeneration. Here, his research focuses on age-related ECM remodeling and related longevity interventions. We caught up

Rejuvenated skin

Old Human Skin Rejuvenated When Implanted in Young Mice

Publishing in Science, researchers have transplanted old human skin to young mice and witnessed a robust rejuvenation cascade that is probably triggered by vascular growth [1]. New life for old skin Our skin begins to age relatively early, and this conspicuous process gave rise to a

Rejuvenation Roundup June

Rejuvenation Roundup June 2022

As rejuvenation biotechnology begins to take root, more and more biotech companies are joining the fight against aging. Here’s what’s happened in research, development, investment, and advocacy last month. LEAF News Our fifth annual conference, Ending Age-Related Diseases 2022, will be coming up next month. Our

Older people running

Metformin Is Linked to Weaker Exercise Improvements

A study published in Obesity suggests that metformin may decrease the gains in cardiorespiratory performance brought on by exercise. The world’s most common diabetes drug Metabolic syndrome, which is represented by the four connected symptoms of obesity, excessive fats in the bloodstream (dyslipidemia), high blood pressure

Natasha Vita-More

H+ DAO and Transhumanism with Dr. Natasha Vita-More

“Transhumanism is a philosophy, worldview, and a movement,” Dr. Natasha Vita-More states in the book “Transhumanism: What is it?” Essentially, it’s the idea of being able to move beyond being human, and finding solutions to living longer, healthier lives. Natasha is an Executive Director of Humanity+,

DNA Details

Longevity Through Altering Essential Gene Expression

In a new study published in GeroScience, researchers have shown that it is possible to significantly increase yeast lifespan by overexpressing genes highly conserved across various species [1]. Survival and aging The question of the effects of nature versus nurture, or programmed versus stochastic, sparks hot

Cocoa

Cocoa Extract Reduces Cardiovascular Mortality

A large-scale, randomized, controlled trial has found that in aging adults, cocoa extract does not affect the prevalence of adverse cardiovascular events but decreases their lethality [1]. Rich in flavanols The nutrients that we consume obviously impact our healthspan and lifespan, but studying their effects in

Elderly eating healthy

The Relationship Between Diet and Senescence

An extremely comprehensive review published in Food Science & Biotechnology has summarized the current state of research regarding cellular senescence and basic dietary components. An aging-focused outlook The researchers begin their paper with a discussion of aging, citing a paper that frames it in terms of

Senolytic Helps Anti-Osteoarthritis Potential in Stem Cells

Scientists have improved the potential effectiveness of a stem cell therapy for osteoarthritis by targeting senescent cells [1]. Stem cell exhaustion and osteoarthritis Osteoarthritis is an age-related disease that affects joints by degrading cartilage. While not fatal in itself, osteoarthritis negatively affects mobility and quality of

Strong mouse

Stem Cells for Fighting Sarcopenia

In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple uses As multipotent stem cells, MSCs can differentiate into several different cell types, including fat cells,