Category: News
Research, DeSci, and Advocacy at Longevity Summit Dublin
September 27, 2022
It was all about collaboration: maybe not a lot of shiny new discoveries and unpublished data, but Longevity Summit Dublin 2022 brought together researchers, investors, and advocates to forge a
Fundamental Metabolic Changes Accompany Alzheimer’s Disease
September 26, 2022
A paper published in Cell Metabolism has reported on a metabolic shift in neurons derived from patients with Alzheimer’s disease, showing that they express a cancer-like phenotype [1]. Induced neurons
A Wearable Tracker For Metabolites, Nutrients, and Drugs
September 23, 2022
Today, we want to highlight an interesting development on the wearable diagnostic front: researchers have developed a wearable device that can monitor nutrients, hormones, and drugs [1]. Real-time health monitoring
Transplanting B Cells from Old to Young Mice Improves Them
September 22, 2022
Researchers have recently explored why B cells become less efficient as we age, analyzing how their behavior changes when they are transplanted from aged mice into young mice [1]. The
One Drug to Fight Both Sarcopenia and Osteoporosis
September 21, 2022
In a new study published in Bone Research, Japanese researchers established a novel drug screening system and identified a promising compound to treat age-associated muscle and bone frailty [1]. Musculoskeletal
Early-Onset Cancer Cases Are Rising
September 20, 2022
In a review paper published in Nature, scientists discuss the problem of the rising burden of early-onset cancer [1]. Not just a disease of aging We tend to think of
Inflammation Linked To Alzheimer’s and Parkinson’s
September 19, 2022
In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on
Multivitamin Supplementation Shown to Improve Cognition
September 16, 2022
In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one
Stem Cell Activity Regulated By Mitochondrial Protein
September 15, 2022
Researchers publishing in Cell Stem Cell have found that the mitochondrial protein OPA1 is an integral, regulatory part of muscle stem cell activation, the process by which muscle stem cells
Removing Senescent Cells to Alleviate Muscular Dystrophy
September 14, 2022
A study published in Aging has shown that the removal of senescent cells through senolytics alleviates muscle degeneration in a mouse model of Duchenne muscular dystrophy. A genetic disease with
Neuromodulation Improves Memory in Older Adults
September 14, 2022
A new study published in Nature Neuroscience has shown that neuromodulation of low-frequency neuronal activity in the parietal cortex improved working memory, while high-frequency modulation in the prefrontal cortex improved
Injectable Cytokine Factories Eradicate Cancer in Mice
September 13, 2022
Researchers have succeeded in beating a type of cancer previously considered incurable by using microcapsules that contained live cytokine-producing cells [1]. IL-2 is potent but toxic Interleukin-2 (IL-2) therapy was
Ketogenic and Mediterranean Diets Effective Against Diabetes
September 12, 2022
Pitting a ketogenic diet against a Mediterranean diet in pre-diabetes and Type 2 diabetes patients, scientists have learned that both confer metabolic benefits, but “keto” also has a darker side
Lactate Inhibits Tumor Growth in Mice
September 9, 2022
Publishing in Nature, scientists have found that sodium lactate boosts the T cell-mediated anti-cancer immune response, leading to significant inhibition of tumor growth [1]. A double-edged sword As a means
Senescence-Associated Protein Promotes Skin Aging in Mice
September 8, 2022
Researchers publishing in Aging have identified an individual protein, secreted frizzled-related protein 4 (SFRP4), that is produced by senescent cells and contributes to skin aging in mice. The spread of
Research, DeSci, and Advocacy at Longevity Summit Dublin
September 27, 2022
It was all about collaboration: maybe not a lot of shiny new discoveries and unpublished data, but Longevity Summit Dublin 2022 brought together researchers, investors, and advocates to forge a common vision. More attention is being brought to the last category, as evidenced by our own
Fundamental Metabolic Changes Accompany Alzheimer’s Disease
September 26, 2022
A paper published in Cell Metabolism has reported on a metabolic shift in neurons derived from patients with Alzheimer’s disease, showing that they express a cancer-like phenotype [1]. Induced neurons Rather than attempting to harvest live neurons from Alzheimer’s patients, the researchers chose to create induced
A Wearable Tracker For Metabolites, Nutrients, and Drugs
September 23, 2022
Today, we want to highlight an interesting development on the wearable diagnostic front: researchers have developed a wearable device that can monitor nutrients, hormones, and drugs [1]. Real-time health monitoring The popularity of medical wearables has increased in recent years. A few decades ago, a complex
Transplanting B Cells from Old to Young Mice Improves Them
September 22, 2022
Researchers have recently explored why B cells become less efficient as we age, analyzing how their behavior changes when they are transplanted from aged mice into young mice [1]. The immune system is a comprehensive defense system Our immune systems protect us from disease and are
One Drug to Fight Both Sarcopenia and Osteoporosis
September 21, 2022
In a new study published in Bone Research, Japanese researchers established a novel drug screening system and identified a promising compound to treat age-associated muscle and bone frailty [1]. Musculoskeletal system Muscle health and bone health are tightly interconnected. Various muscular dystrophies are a great example:
Early-Onset Cancer Cases Are Rising
September 20, 2022
In a review paper published in Nature, scientists discuss the problem of the rising burden of early-onset cancer [1]. Not just a disease of aging We tend to think of cancer of a disease of aging, and for a good reason: cancer is indeed highly correlated
Inflammation Linked To Alzheimer’s and Parkinson’s
September 19, 2022
In the Journal of Inflammation, researchers from Johns Hopkins University have published a detailed review of the relationship between brain inflammation and the principal diseases of dementia. A focus on genetics and environment One out of twenty Americans over 85 have Parkinson’s disease [1], and seven
Multivitamin Supplementation Shown to Improve Cognition
September 16, 2022
In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one study Multivitamins are among the most popular dietary supplements, but their effectiveness is often questioned. While
Stem Cell Activity Regulated By Mitochondrial Protein
September 15, 2022
Researchers publishing in Cell Stem Cell have found that the mitochondrial protein OPA1 is an integral, regulatory part of muscle stem cell activation, the process by which muscle stem cells proliferate and become active muscle tissue (myogenesis) [1]. Another piece of the puzzle We have recently
Removing Senescent Cells to Alleviate Muscular Dystrophy
September 14, 2022
A study published in Aging has shown that the removal of senescent cells through senolytics alleviates muscle degeneration in a mouse model of Duchenne muscular dystrophy. A genetic disease with hallmarks of aging Duchenne muscular dystrophy is caused by a mutation that gradually destroys the muscles,
Neuromodulation Improves Memory in Older Adults
September 14, 2022
A new study published in Nature Neuroscience has shown that neuromodulation of low-frequency neuronal activity in the parietal cortex improved working memory, while high-frequency modulation in the prefrontal cortex improved long-term memory in older adults [1]. As people age, their cognitive abilities get worse. This includes
Injectable Cytokine Factories Eradicate Cancer in Mice
September 13, 2022
Researchers have succeeded in beating a type of cancer previously considered incurable by using microcapsules that contained live cytokine-producing cells [1]. IL-2 is potent but toxic Interleukin-2 (IL-2) therapy was the first anti-cancer immunotherapy approved decades ago. It is based on the ability of this inflammatory
Ketogenic and Mediterranean Diets Effective Against Diabetes
September 12, 2022
Pitting a ketogenic diet against a Mediterranean diet in pre-diabetes and Type 2 diabetes patients, scientists have learned that both confer metabolic benefits, but “keto” also has a darker side [1]. Diabetes is often reversible with diet While many anti-diabetes drugs have been developed in recent
Lactate Inhibits Tumor Growth in Mice
September 9, 2022
Publishing in Nature, scientists have found that sodium lactate boosts the T cell-mediated anti-cancer immune response, leading to significant inhibition of tumor growth [1]. A double-edged sword As a means of energy production, the Krebs cycle is preferred by most cells in most conditions. However, there
Senescence-Associated Protein Promotes Skin Aging in Mice
September 8, 2022
Researchers publishing in Aging have identified an individual protein, secreted frizzled-related protein 4 (SFRP4), that is produced by senescent cells and contributes to skin aging in mice. The spread of the SASP The authors of this paper introduce this topic with a familiar discussion of the