Here at lifespan.io we are working to overcome age-related diseases such as Alzheimer’s, cancer, and heart disease, by raising funds and awareness for credible research that addresses the root causes of the aging process.
By using the Tabs for Life Chrome extension you are helping to support our mission, as revenue from the banner ads on this page will support our 501(c)(3) charity organization LEAF.
Please feel free to learn more by browsing this website, and see the latest scientific news on biotechnology aimed at extending healthy human lifespan below.
STAY INFORMED WITH TABS FOR LIFE
Rejuvenation Roundup April 2026
Aging is a multifaceted topic, and it’s becoming more and more clear that the only way to deal with it is piece by piece. Here’s what pieces our industry has put together in April. Advocacy
Some Researchers Choose Replacement Over Repair in Aging
A perspective published in Aging Cell details the replacement-based approaches being investigated by several research organizations. Repair versus replacement This perspective begins by noting the inherent difficulty of rejuvenating the human body because of the
Daytime Napping and Mortality Association in Older Adults
A recent study found an association between longer and more frequent daytime napping and higher mortality risk. The authors suggest using napping frequency and duration as behavioral markers of increased mortality risk [1]. Common activity
A Popular Senolytic Treatment Causes Brain Damage in Mice
A new study calls for caution in using the well-known senolytic treatment of dasatinib and quercetin (D+Q), showing that it causes damage in certain regions of the brain, similar to what is observed in multiple
Obesity’s Effects on the Immune System May Linger for Years
A new study has suggested that T cells might retain a pro-inflammatory phenotype long after normal weight is regained following a period of obesity. In mice, the effect lasts for weeks, while its existence and
A Robust Senescence Response Helps Wounds Heal
A team of scientists has examined how younger and older mice heal from wounds and found that more robust senescent cell activation in younger animals helps them heal faster. A double-edged sword Multiple experiments have
Reprogrammed Cardiomyocytes Soften the Blow in Heart Attack
A new study has found that partial reprogramming mitigates the damage of myocardial infarction in mice by helping heart muscle cells to complete division [1]. When heart cells get stuck When a heart attack (myocardial
It’s Springtime and the Rejuvenation Field Is Flourishing
For those of us in the Northern Hemisphere, spring is here. This is a time of renewal and hope for better times ahead, echoing what our field is trying to achieve: the rejuvenation of aging
Longevity Day at NFC Summit Lisbon Announces Speaker Lineup
Longevity Day at NFC Summit Lisbon has announced its confirmed speaker lineup ahead of its debut on 4 June 2026 at the Unicorn Factory in Lisbon. The event will bring together scientists, clinicians, founders, and
The Immune System Ages Differently in Men and Women
An investigation into the aging immune system identified age-related changes, including sex-dependent differences, in immune cell subpopulations and gene expression. In general, females showed greater age-related changes than males, including greater changes in autoimmune gene
Rapamycin Might Blunt Exercise Response in Humans
According to a new study, rapamycin probably interferes with exercise, blunting its effects in older human subjects. This result, however, might be specific to the particular protocol. Can they work together? Physical activity is one
BioAge Reports Positive Phase 1 Data for BGE-102
BioAge Labs, Inc. (Nasdaq: BIOA) (“BioAge” or the “Company”), a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases by targeting the biology of human aging, today reported results from the Phase 1 clinical
How Inflammaging Is Linked to Epigenetic Aging
A paper in Cell Genomics has described how age-related systemic inflammation (inflammaging) is related to epigenetic aging as measured by four established clocks. Tying together two well-known aspects of aging These researchers note that inflammatory
Engineered Stem Cells Become Lifelong Protein Factories
Researchers have genetically engineered blood stem cells to produce B cells that can churn out rare broad-action antibodies to fight HIV, malaria, and flu. This platform can also be used to produce other essential proteins
Targeting an Appetite Hormone Receptor for Stronger Muscles
In Aging Cell, researchers have described how suppressing the ghrelin receptor improves muscle function and fights sarcopenia in older mice. An appetite hormone with negative effects Ghrelin has been well-documented as stimulating both appetite and
Vitamin C Alleviates Aging in Cynomolgus Monkeys
A recent study described a process called ferro-aging, in which iron accumulation leads to oxidative damage and cellular senescence. This process can be delayed by Vitamin C [1]. A two-faced atom Iron, like many components
A Single Sauna Session Causes White Blood Cell Mobilization
A new study shows that hitting a sauna for 30 minutes causes a transient spike in the number of circulating white blood cells. The researchers suggest that this exercise-like effect might provide health benefits by
Why Fast-Cycling Skin Cells Decrease With Age
In Aging Cell, researchers have described how one dermal protein is related to maintaining the populations of fast-cycling skin cells and preserving skin integrity. Not all skin cells are the same The outer layer of
APLMS and Kitalys to Host Healthy Longevity in Hong Kong
The Asia-Pacific Longevity Medicine Society (APLMS), in partnership with The Kitalys Institute, announced that the 2026 Asia-Pacific Healthy Longevity International Summit (APAC-LMIS) will be held in Hong Kong from October 1–4, 2026, at the Hopewell
Affecting a Signaling Pathway Alleviates Alzheimer’s in Mice
A new study shows that the overexpression of somatostatin (SST), a neuropeptide produced in neurons and acting mostly on microglia, lowers inflammation and amyloid β burden, improving cognitive abilities in a mouse model of Alzheimer’s.
A Combination NAD+ Treatment Has Benefits for Mice
Researchers have found that simultaneously supplying NAD+ through NMN and reducing its loss through apigenin restores muscle function and bone structure to aged mice. A well-documented issue NAD+ is one of the most well-documented compounds
Life Bio’s Trial: Is the FDA Warming to Rejuvenation?
The FDA views aging as an inevitability, not a medical target. However, with Life Biosciences moving the first cellular reprogramming therapy into human trials this year, things might be changing there. If this technique works
The Timing of Meals Matters for Biological Aging
A recent study investigated a connection between the timing of meals and the rate of biological aging. These findings suggest that later timing of the first and last meals is associated with faster aging [1].
APOE4 Increases Neurons’ Excitability Before Symptoms Appear
The pro-Alzheimer’s allele APOE4 makes hippocampal neurons in mice smaller and hyperexcitable. This effect, which resembles epilepsy and accelerated aging, can be mitigated by manipulating a neuronal protein [1]. Before symptoms arise Alzheimer’s disease begins
A Target for Ameliorating Post-Operative Delirium
Researchers have discovered a potential treatment for post-operative delirium, which accelerates cognitive decline in older people. A common problem with long-term effects Roughly a quarter of older people suffer from delirium after surgery [1], which
Insilico and Eli Lilly Announce a Major Collaboration
Building on two previous deals between the companies, this new agreement is potentially worth up to $2.75 billion and involves Lilly licensing assets from Insilico’s pipeline. More than software Earlier this week, the AI-driven drug
How an Enzyme’s Depletion Makes Fat Worse
In Aging Cell, researchers have described how the enzyme Pck1, a core part of metabolic activity, is required for staving off senescence in fat (adipose) cells. The aging of fat With the decrease in metabolic
Becoming Well-Fed and Sedentary Accelerates Penguin Aging
A recent study suggests that the transition of king penguins from the wild to a zoo environment, which resembles a sedentary, well-fed Western lifestyle, results in accelerated aging and changes in metabolic pathways [1]. A
Rejuvenation Roundup March 2026
For many hundreds of years, Easter has been associated with rebirth and rejuvenation. Let’s see what’s been done last month to rejuvenate animals and people. Team and Activities Support the Human Ageing Genomic Resources: João
Modified Immune Cells Target Cancer’s Metabolic Signature
Arming NK and T cells with metabolite-sensing receptors enhances their ability to infiltrate tumors and improves cancer outcomes in mice in a new study [1]. How to get immune cells into the tumor? One of